Nokea
The nurse is caring for a patient who is experiencing an immune response involving B and T cells. Which type of immunity is the patient demonstrating?
- A. Passive immunity
- B. Humoral immunity
- C. Acquired immunity
- D. Cell-mediated immunity
Correct Answer: B
Rationale: The correct answer is B: Humoral immunity. Humoral immunity involves B cells producing antibodies to target pathogens. B cells are responsible for producing antibodies that circulate in the blood and lymph to neutralize pathogens. This type of immunity is specific to antigens and is a key component of the adaptive immune response. Passive immunity (A) is when antibodies are transferred from one individual to another, not involving B and T cells directly. Acquired immunity (C) is a broad term encompassing both humoral and cell-mediated immunity. Cell-mediated immunity (D) involves T cells directly targeting infected cells, not B cells producing antibodies.
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When a patient is undergoing brachytherapy, what is it important for the nurse to be aware of when caring for this patient?
- A. The patient will undergo simulation to identify and mark the field of treatment
- B. The patient is a source of radiation and personnel must wear film badges during care
- C. The goal of this treatment is only palliative and the patient should be aware of the expected outcome
- D. Computerized dosimetry is used to determine the maximum dose of radiation to the tumor within an acceptable dose to normal tissue
Correct Answer: B
Rationale: Patients undergoing brachytherapy emit radiation, requiring safety measures for healthcare providers.
Which of the following is NOT true about multiple sclerosis (MS)
- A. Sex bias observed with males more at risk of developing the disease
- B. Incidence higher in northern countries
- C. Symptoms caused by demyelination of neurons
- D. EAE is an animal model for MS induced by injection with myelin
Correct Answer: A
Rationale: The correct answer is A: Sex bias observed with males more at risk of developing the disease. This statement is NOT true because MS actually has a sex bias towards females, with women being more at risk. This is due to hormonal, genetic, and immunological factors. The other choices are true: B is correct as MS is more common in northern regions, possibly due to environmental factors; C is correct since MS is characterized by demyelination of neurons leading to various symptoms; and D is correct as experimental autoimmune encephalomyelitis (EAE) is an animal model often used to study MS, induced by injecting myelin components to trigger an immune response.
Patients with rheumatoid arthritis typically have pain:
- A. With activity.
- B. Upon awakening.
- C. Late in the evening.
- D. All day without remission.
Correct Answer: B
Rationale: Rheumatoid arthritis often causes morning stiffness and pain upon awakening due to inflammation and lack of movement during sleep. Pain tends to improve with activity as joints warm up.
Which of the following is a characteristic of the constant region of a T cell receptor?
- A. Mediates antigen binding
- B. Anchors the receptor in the T cell membrane
- C. Interacts with MHC molecules
- D. Structurally diverse amongst all T cell receptors
Correct Answer: B
Rationale: The correct answer is B: Anchors the receptor in the T cell membrane. The constant region of a T cell receptor is responsible for anchoring the receptor in the T cell membrane, providing stability and structural support. This region does not mediate antigen binding (choice A), as that function is carried out by the variable region. It also does not directly interact with MHC molecules (choice C), which is primarily the role of the variable region. Lastly, the constant region is not structurally diverse amongst T cell receptors (choice D), as it remains relatively consistent within a specific T cell subtype.
Which of the following cells are 'professional' antigen presenting cells
- A. Neutrophils, dendritic cells, B cells
- B. B cells, T cells, dendritic cells
- C. Macrophages, B cells, dendritic cells
- D. Neutrophils, epithelial cells, dendritic cells
Correct Answer: C
Rationale: The correct answer is C: Macrophages, B cells, dendritic cells. Professional antigen-presenting cells are specialized immune cells that effectively present antigens to T cells. Macrophages, B cells, and dendritic cells are considered professional APCs because they express major histocompatibility complex (MHC) molecules and co-stimulatory molecules, allowing them to effectively activate T cells. Neutrophils and epithelial cells are not considered professional APCs as they have limited ability to present antigens to T cells. B cells and T cells are not APCs themselves, but B cells can act as APCs when they present antigens to T cells in the context of an immune response.