Nokea
The nurse is teaching a nursing student about the antifungal drug amphotericin B. Which statement by the student indicates a need for further teaching?
- A. Amphotericin B may be given intravenously or by mouth
- B. Patients who take this drug should have potassium and magnesium levels assessed
- C. Patients with renal disease should not take amphotericin B
- D. This drug is used for severe systemic infections
Correct Answer: A
Rationale: Amphotericin B is IV-only due to poor oral absorption; electrolyte monitoring and systemic use are correct. Amphotericin B is not absorbed from the gastrointestinal tract, so is not given by mouth.
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The following can be used for diabetes mellitus:
- A. Desmoporesine
- B. Insuline preparations
- C. Chlorpropamide
- D. Metformin
Correct Answer: A
Rationale: Insulin, chlorpropamide, metformin, and acarbose (B, C, D, E) are all used for diabetes management.
It is customary to administer systemic corticosteroids early in the morning because:
- A. This prevents early morning bronchospasms
- B. To inhibit adrenocorticotrophic hormone over secretion
- C. To achieve high plasma concentrations throughout the day
- D. To prevent adrenocortex suppression
Correct Answer: D
Rationale: Morning dosing aligns with cortisol peaks, minimizing adrenal suppression.
45 year old female has a diabetes mellitus. Endocrinologist prescribes treatment, which has a side effect as hypoglycemia and weight gain. Which of the following drug is prescribed?
- A. Canagliflozin
- B. Exenatide
- C. Gliburide
- D. Pramlintide
Correct Answer: C
Rationale: Gliburide, a sulfonylurea, commonly causes hypoglycemia and weight gain due to increased insulin release.
Which of the following statements about beta-blockers is false?
- A. Beta-blockers should be avoided with non-dihydropyridine calcium channel blockers
- B. Beta-blockers increase renin secretion
- C. Non-selective beta-blockers are contraindicated in asthma
- D. Beta-blockers prolong the refractory period of the AV node
Correct Answer: B
Rationale: Beta-blockers decrease renin secretion by blocking beta-1 receptors in the kidney, making this statement false.
The nurse is assessing a diabetic patient who has presented at the clinic reporting several hypoglycemic episodes during the past 3 weeks. The nurse questions the patient about the use of herbal or alternative therapies, suspecting what herbal remedy could cause the hypoglycemic episodes?
- A. St. John's wort
- B. Kava
- C. Fish oil
- D. Ginseng
Correct Answer: D
Rationale: Ginseng is known to decrease blood sugar levels. If the patient used this in combination with his or her oral antidiabetic agent, diet, and exercise, his or her blood sugar could drop below therapeutic levels. St. John's wort interacts with many drugs, but not with antidiabetic agents. Kava is associated with liver toxicity. Fish oil has been associated with decreased coronary artery disease.