Endocrine System MCQ Questions Related

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There are two simple ways to lower blood pressure: (1) reduce the cardiac contractility, and (2) inhibit sympathetic-mediated vasoconstriction. Which one of the following drugs can lower blood pressure by both mechanisms?

  • A. Albuterol
  • B. Atropine
  • C. Labetalol
  • D. Isoproterenol
Correct Answer: C

Rationale: Rationale: Labetalol is a non-selective beta-blocker that reduces cardiac contractility by blocking beta-1 receptors and inhibits sympathetic-mediated vasoconstriction by blocking alpha-1 receptors. Albuterol (A) is a beta-2 agonist, which increases cardiac contractility. Atropine (B) is a muscarinic antagonist, which increases heart rate and does not affect vasoconstriction. Isoproterenol (D) is a non-selective beta agonist, which increases cardiac contractility and vasodilation. Thus, C (Labetalol) is the only drug that can lower blood pressure by both mechanisms.