What drives the emergence of immuno-resistant pathogen strains?
- A. Host immune system failure
- B. Slow mutation rates in pathogens
- C. Rapid pathogen reproduction and mutations
- D. Absence of host immune adaptation
Correct Answer: C
Rationale: The correct answer is C: Rapid pathogen reproduction and mutations drive the emergence of immuno-resistant pathogen strains. This is because the high rate of reproduction allows for more opportunities for mutations to occur, some of which may confer resistance to the host's immune system or medical interventions. Slow mutation rates in pathogens (B) would not lead to the rapid emergence of resistant strains. Host immune system failure (A) occurs after the pathogen has already developed resistance. The absence of host immune adaptation (D) does not directly drive the emergence of resistant strains as it is the rapid reproduction and mutations of pathogens that play a crucial role.
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What are the key steps of phagocytosis?
- A. Recognition, digestion, and excretion
- B. Recognition, ingestion, and digestion
- C. Adhesion, secretion, and ingestion
- D. Activation, release, and excretion
Correct Answer: B
Rationale: The correct answer is B: Recognition, ingestion, and digestion. Firstly, recognition is essential for phagocytes to identify and bind to the target. Next, ingestion involves engulfing the target into a phagosome. Finally, digestion occurs within the phagolysosome, where enzymes break down the target. Choices A, C, and D are incorrect because they do not accurately represent the sequential key steps of phagocytosis.
What is the main limitation of innate immunity compared to adaptive immunity?
- A. It cannot produce cytokines
- B. It lacks memory and specificity
- C. It does not include physical barriers
- D. It cannot activate complement
Correct Answer: B
Rationale: The main limitation of innate immunity compared to adaptive immunity is that innate immunity lacks memory and specificity. This means that innate immune responses do not improve upon repeated exposure to the same pathogen and cannot target specific antigens efficiently. Adaptive immunity, on the other hand, can remember previous encounters with pathogens and mount targeted responses. Choices A, C, and D are incorrect because innate immunity can produce cytokines, includes physical barriers like skin and mucous membranes, and can activate complement as part of its defense mechanisms.
Which compounds produced by microorganisms can cause fever in humans and can withstand autoclaving?
- A. endotoxin
- B. Lipid A
- C. lipopolysaccharide
- D. peptidoglycan
Correct Answer: D
Rationale: The correct answer is D, peptidoglycan. Peptidoglycan is a component of bacterial cell walls that can trigger fever in humans. It is a sturdy molecule that can withstand autoclaving.
A: Endotoxin is a component of the outer membrane of Gram-negative bacteria, not resistant to autoclaving.
B: Lipid A is the toxic component of endotoxin, not resistant to autoclaving.
C: Lipopolysaccharide is the major component of the outer membrane of Gram-negative bacteria, not resistant to autoclaving.
A patient with advanced AIDS has a nursing diagnosis of impaired memory related to neurologic changes. In planning care for the patient, what should the nurse set as the highest priority?
- A. Maintain a safe patient environment
- B. Provide a quiet, nonstressful environment to avoid overstimulation
- C. Use memory cues such as calendars and clocks to promote orientation
- D. Provide written instructions of directions to promote understanding and orientation
Correct Answer: A
Rationale: Safety is paramount for cognitively impaired patients. Preventing falls and ensuring access to necessities takes precedence over other interventions.
Priority Decision: The patient with advanced cancer is having difficulty controlling her pain. She says she is afraid she will become addicted to the opioids. What is the first thing the nurse should do for this patient?
- A. Administer a nonsteroidal antiinflammatory drug
- B. Assess the patient’s vital signs and behavior to determine the medication to use
- C. Have the patient keep a pain diary to better assess the patient’s potential addiction
- D. Obtain a detailed pain history including quality,location intensity duration and type of pain
Correct Answer: D
Rationale: A detailed pain history helps tailor pain management strategies and alleviates concerns about addiction.