Nokea
What is a prodrug
- A. Drag which increases efficiency of another drug
- B. Metabolic end product
- C. Inactive drag which gets activated in the body
- D. Drag which competes with another for metabolism
Correct Answer: C
Rationale: A prodrug is inactive until metabolized into an active form in the body.
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A nurse is preparing to administer Propranolol to a client who has a dysrhythmia. Which of the following actions should the nurse plan to take?
- A. Hold propranolol for an apical pulse greater than 100/min.
- B. Administer propranolol to increase the client's blood pressure.
- C. Assist the client when she sits up or stands after taking this medication.
- D. Check for hypokalemia frequently due to the risk for propranolol toxicity.
Correct Answer: C
Rationale: Propranolol can cause orthostatic hypotension; assisting with position changes prevents falls.
Monitoring a patient on a high-dose aspirin level includes:
- A. Salicylate level
- B. Complete blood count
- C. Urine pH
- D. All of the above
Correct Answer: D
Rationale: High-dose aspirin requires salicylate levels , CBC for bleeding, and urine pH for excretion monitoring.
The nurse is teaching a nursing student about the antifungal drug amphotericin B. Which statement by the student indicates a need for further teaching?
- A. Amphotericin B may be given intravenously or by mouth
- B. Patients who take this drug should have potassium and magnesium levels assessed
- C. Patients with renal disease should not take amphotericin B
- D. This drug is used for severe systemic infections
Correct Answer: A
Rationale: Amphotericin B is IV-only due to poor oral absorption; electrolyte monitoring and systemic use are correct. Amphotericin B is not absorbed from the gastrointestinal tract, so is not given by mouth.
Which one of the following statements is NOT true of warfarin?
- A. It is extensively 99% bound to plasma albumin
- B. Its use in pregnant women is contraindicated because it is teratogenic
- C. It is active in vitro
- D. Its induced bleeding can be conteracted by treatment with phytonadione
Correct Answer: C
Rationale: Warfarin acts in vivo by inhibiting vitamin K epoxide reductase, not in vitro; thus, is false.
The following can be used for diabetes mellitus:
- A. Desmoporesine
- B. Insuline preparations
- C. Chlorpropamide
- D. Metformin
Correct Answer: A
Rationale: Insulin, chlorpropamide, metformin, and acarbose (B, C, D, E) are all used for diabetes management.