What is the patient with chronic pancreatitis more likely to have than the patient with acute pancreatitis?
- A. The need to abstain from alcohol
- B. Experience acute abdominal pain
- C. Malabsorption and diabetes mellitus
- D. Require a high-carbohydrate, high-protein, low-fat diet
Correct Answer: C
Rationale: Chronic pancreatitis often leads to malabsorption and diabetes mellitus due to long-term pancreatic dysfunction.
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The major part of the aqueous component (other than water) of pancreatic juice is
- A. mucus.
- B. trypsinogen, chymotrypsinogen, and procarboxypeptidase.
- C. bicarbonate ions.
- D. secretin.
Correct Answer: C
Rationale: The correct answer is C: bicarbonate ions. Pancreatic juice is alkaline to neutralize the acidic chyme entering the small intestine from the stomach. Bicarbonate ions are secreted by pancreatic duct cells and play a major role in maintaining the pH balance. Mucus (choice A) is produced by goblet cells and helps protect the lining of the digestive tract but is not a major component of pancreatic juice. Trypsinogen, chymotrypsinogen, and procarboxypeptidase (choice B) are pancreatic enzymes, not the major component of the aqueous component. Secretin (choice D) is a hormone that stimulates the pancreas to release bicarbonate ions but is not a component of pancreatic juice itself.
Patients with gastric ulcer typically exhibit the following symptoms:
- A. Epigastric pain worse after eating and weight loss.
- B. Epigastric pain worse before meals, pain awakening patient from sleep, and melena.
- C. Decreased bowel sounds, rigid abdomen, rebound tenderness, and fever.
- D. Boring epigastric pain radiating to back and left shoulder, bluish-gray discoloration of periumbilical area, and ascites.
Correct Answer: B
Rationale: Gastric ulcers typically present with epigastric pain that worsens before meals, pain that can wake the patient at night, and melena due to gastrointestinal bleeding.
Which of the following statements regarding caloric restriction (CR) is TRUE?
- A. CR stimulates the insulin signalling pathway, leading to activation of longevity genes
- B. resveratrol can mimic the effects of caloric restriction in worms, yeast and flies
- C. CR has been demonstrated to increase life span in humans
- D. all of the above are true
Correct Answer: B
Rationale: The correct answer is B: Resveratrol can mimic the effects of caloric restriction in worms, yeast, and flies. This is true because resveratrol, a compound found in red wine, has been shown to activate certain proteins and enzymes that are also activated during caloric restriction, leading to improved health and longevity in these organisms.
A is incorrect because caloric restriction typically leads to decreased insulin signaling, not stimulation. C is incorrect because while CR has been shown to increase lifespan in various animal models, there is limited evidence to support its effects on human lifespan. D is incorrect because not all statements are true - only B is supported by scientific evidence.
What is the role of the large intestine?
- A. digestion of proteins
- B. absorption of nutrients
- C. absorption of water
- D. production of bile
Correct Answer: C
Rationale: The large intestine's main role is to absorb water from the indigestible food residue, forming feces. This process helps maintain proper hydration levels in the body. It does not digest proteins (choice A) or absorb nutrients (choice B), as these processes primarily occur in the small intestine. The production of bile (choice D) is carried out by the liver and stored in the gallbladder, not by the large intestine. Thus, choice C is correct as it aligns with the primary function of the large intestine.
Which characterizes auscultation of the abdomen?
- A. The presence of borborygmi indicates hyperperistalsis.
- B. The bell of the stethoscope is used to auscultate high-pitched sounds.
- C. High-pitched
- D. rushing
Correct Answer: A
Rationale: Borborygmi is the sound of hyperperistalsis often heard when the stomach is actively moving food.