Immune System Quizlet Related

Review Immune System Quizlet related questions and content

What is the typical outcome of a C1q deficiency in the complement system?

  • A. Enhanced inflammation
  • B. Reduced phagocytosis
  • C. Autoimmune diseases such as SLE
  • D. Increased cancer risk
Correct Answer: C

Rationale: The correct answer is C: Autoimmune diseases such as SLE. C1q is essential for the classical pathway of the complement system, which plays a crucial role in clearing immune complexes. A deficiency in C1q can lead to impaired immune complex clearance, resulting in the development of autoimmune diseases like Systemic Lupus Erythematosus (SLE).

Choice A (Enhanced inflammation) is incorrect because a deficiency in C1q would actually lead to decreased inflammation due to impaired complement activation.

Choice B (Reduced phagocytosis) is incorrect because phagocytosis is primarily mediated by the alternative pathway of the complement system, not the classical pathway involving C1q.

Choice D (Increased cancer risk) is incorrect as C1q deficiency is not directly associated with an increased risk of cancer.