When writing a prescription for warfarin it is common to write ____ on the prescription.
- A. OK to substitute for generic
- B. The brand name of warfarin and Do Not Substitute
- C. PRN refills
- D. Refills for 1 year
Correct Answer: B
Rationale: Brand-specific warfarin ensures consistent potency; generics vary slightly, and PRN or yearly refills are impractical.
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Drug levels should be monitored in the treatment of
- A. Diabetes
- B. Epilepsy
- C. Status Asthmatics
- D. Hypertension
Correct Answer: B
Rationale: Therapeutic drug monitoring is critical in epilepsy (e.g., phenytoin) due to narrow therapeutic ranges.
The nurse, working on the maternity unit, receives a call from a pregnant woman asking how she can know whether a medication is safe to take while pregnant. What is the nurses best response?
- A. You can take any drug indicated as a Category A.
- B. No medications should be taken during pregnancy.
- C. Never take medication until you receive approval from your health care provider.
- D. Most medications are safe but you need to weigh benefit against risk.
Correct Answer: C
Rationale: The best response to a pregnant woman asking about medication usage is to talk with her obstetric practitioner because the best advice will come from someone who knows their health and pregnancy history. While Category A drugs have no known risk, they may be contraindicated by the woman's health condition or pregnancy issues and many pregnant women would not know what it means to be a Category A drug. Medications can be helpful during pregnancy if taken safely and appropriately. Although risk benefit needs to be weighed, it should occur with advice from the obstetric practitioner.
Which diuretic is classified as a thiazide?
- A. Furosemide
- B. Spironolactone
- C. Hydrochlorothiazide
- D. Mannitol
Correct Answer: C
Rationale: Hydrochlorothiazide is a thiazide diuretic, acting on the distal convoluted tubule, unlike furosemide (loop), spironolactone (potassium-sparing), or mannitol (osmotic).
Which of the following concepts is considered when generic drugs are substituted for brand-name drugs?
- A. Bioavailability
- B. Critical concentration
- C. Distribution
- D. Half-life
Correct Answer: A
Rationale: Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available to act on body cells. Binders used in a generic drug may not be the same as those used in the brand-name drug. Therefore, the way the body breaks down and absorbs the drug may differ, affecting its bioavailability.
Patient education regarding the use of ciprofloxacin-hydrocortisone (Cipro HC otic) ear drops includes:
- A. Fill the canal with the drops with each dose
- B. Some redness and itching around the ear canal is normal
- C. Warm the bottle of ear drops in his or her hand before administering
- D. Cipro HC otic may cause ototoxicity
Correct Answer: C
Rationale: Warming Cipro HC improves comfort; filling or ototoxicity aren't standard advice.