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Which bacteria are responsible for causing pneumonia?
- A. Streptococcus pneumoniae
- B. Mycobacterium tuberculosis
- C. Pseudomonas aeruginosa
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D (All of the above) because different bacteria can cause pneumonia. Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. Mycobacterium tuberculosis causes tuberculosis, which can lead to pneumonia. Pseudomonas aeruginosa is a common cause of hospital-acquired pneumonia. Therefore, all three bacteria can be responsible for causing pneumonia in different contexts. Choices A, B, and C are incorrect because each bacterium individually can cause pneumonia, so selecting only one option would not cover the full spectrum of bacterial causes of pneumonia.
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Which of the following is likely to be the most frequently used portal of entry for pathogens?
- A. Skin
- B. Gastrointestinal tract
- C. Respiratory tract
- D. Conjunctiva
Correct Answer: C
Rationale: The correct answer is C: Respiratory tract. The respiratory tract is likely the most frequently used portal of entry for pathogens because it is constantly exposed to the external environment and has a large surface area lined with mucous membranes that can trap and facilitate the entry of pathogens. Additionally, the respiratory tract serves as a direct pathway for pathogens to reach the bloodstream and other organs. Skin (choice A) is a physical barrier that can prevent pathogen entry, while the gastrointestinal tract (choice B) has acidic pH and enzymes that can kill many pathogens. Conjunctiva (choice D) is a less common portal of entry compared to the respiratory tract due to its smaller surface area and protective mechanisms such as tears.
A phage in a repressed stage is referred to as a(n)
- A. antiphage.
- B. prophage.
- C. virulent phage.
- D. latent phage.
Correct Answer: B
Rationale: The correct answer is B: prophage. In the repressed stage, a phage integrates its DNA into the host cell's chromosome, becoming a prophage. This integration allows the phage to replicate along with the host cell without causing immediate lysis.
A: Antiphage is not a term used to describe a phage in a repressed stage.
C: Virulent phage refers to a phage that immediately causes lysis of the host cell.
D: Latent phage is not a commonly used term in this context.
Sterilization destroys all microorganisms including:
- A. vegetative cells only
- B. viruses only
- C. spores
- D. protozoa only
Correct Answer: C
Rationale: Sterilization refers to the complete elimination of all microorganisms, including their spores, which are the most resistant form of microbial life. Spores have a tough outer coating that protects them from harsh conditions, making them more difficult to destroy compared to vegetative cells, viruses, and protozoa. Therefore, the correct answer is C because sterilization targets and eliminates all forms of microorganisms, including spores. Choices A, B, and D are incorrect because sterilization goes beyond just targeting vegetative cells, viruses, or protozoa; it aims to eliminate all microorganisms present.
Enzymes that remove functional groups from a substrate without adding water, or that add functional groups to a double bond, are called
- A. oxidoreductases.
- B. transferases.
- C. hydrolases.
- D. lyases.
Correct Answer: D
Rationale: The correct answer is D: lyases. Lyases are enzymes that catalyze the breaking of chemical bonds without the addition of water. They can remove functional groups from substrates or add functional groups to double bonds without the use of water.
A: Oxidoreductases involve the transfer of electrons.
B: Transferases transfer functional groups from one molecule to another.
C: Hydrolases catalyze the breaking of bonds by adding water.
A patient with fever, enlarged lymph nodes, and bacteremia was diagnosed with plague. The Gram-stained smear revealed bipolar-staining, Gram-negative rods. What is the causative agent?
- A. Yersinia pestis
- B. Francisella tularensis
- C. Brucella abortus
- D. Clostridium botulinum
Correct Answer: A
Rationale: The correct answer is A: Yersinia pestis. Y. pestis is the causative agent of plague, characterized by fever, enlarged lymph nodes, and bacteremia. The bipolar-staining, Gram-negative rods seen on Gram stain are typical of Y. pestis.
Incorrect choices:
B: Francisella tularensis causes tularemia, not plague.
C: Brucella abortus causes brucellosis, not plague.
D: Clostridium botulinum causes botulism, not plague.
In summary, the key features of the patient's presentation and the Gram stain findings align with Yersinia pestis as the correct causative agent of plague.