Genitourinary Review of Systems Related

Review Genitourinary Review of Systems related questions and content

Which disease causes connective tissue changes that cause glomerulonephritis?

  • A. Gout
  • B. Amyloidosis
  • C. Diabetes mellitus
  • D. Systemic lupus erythematosus
Correct Answer: D

Rationale: The correct answer is D: Systemic lupus erythematosus (SLE). SLE is an autoimmune disease that can affect multiple organs, including the kidneys. In SLE, the immune system attacks healthy tissues, leading to inflammation and damage to the connective tissues in the kidneys, resulting in glomerulonephritis. Gout (A) is a form of arthritis caused by the buildup of uric acid crystals, not directly related to glomerulonephritis. Amyloidosis (B) is a condition where abnormal protein deposits can accumulate in organs, but it does not primarily cause glomerulonephritis. Diabetes mellitus (C) can lead to diabetic nephropathy, a common cause of kidney damage, but it does not directly cause glomerulonephritis associated with connective tissue changes.