Which hormone is most important in insulin secretion?
- A. gastrin
- B. CCK
- C. GIP
- D. secretin
Correct Answer: C
Rationale: The correct answer is C: GIP. GIP, or glucose-dependent insulinotropic peptide, is the most important hormone in insulin secretion. It is released by the intestines in response to glucose intake, stimulating the release of insulin from the pancreas. Gastrin (A) is involved in gastric acid secretion, not insulin. CCK (B) and secretin (D) are involved in digestion and pancreatic enzyme secretion, not insulin regulation. So, GIP is the correct answer as it directly stimulates insulin release in response to glucose levels.
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Chief cells secrete:
- A. HCl
- B. pepsinogen
- C. intrinsic factor
- D. HCO3-
Correct Answer: B
Rationale: Chief cells in the gastric glands of the stomach secrete pepsinogen. Pepsinogen is an inactive precursor of pepsin, which is an enzyme responsible for breaking down proteins. This process aids in the digestion of proteins in the stomach. Chief cells do not secrete HCl (A), which is secreted by parietal cells. Intrinsic factor (C) is secreted by parietal cells and is essential for vitamin B12 absorption, not by chief cells. HCO3- (D) is secreted by the pancreas to neutralize stomach acid in the duodenum, not by chief cells in the stomach.
The second-messenger mechanism of hormone action operates by ________.
- A. synthesizing more of the hormone than is actually needed
- B. increasing the basal metabolic rate in the target organ
- C. not responding to a feedback mechanism
- D. binding to specific receptors and employing the services of G proteins and cAMP
Correct Answer: D
Rationale: The correct answer is D because the second-messenger mechanism involves the hormone binding to specific receptors on the cell surface, activating G proteins, which then trigger the production of cyclic adenosine monophosphate (cAMP) inside the cell. cAMP acts as a secondary messenger to relay the hormone's signal and initiate a cellular response. Synthesizing more hormone than needed (A) is not related to the mechanism. Increasing basal metabolic rate (B) is not a direct result of the second-messenger system. Not responding to feedback (C) contradicts the regulatory nature of hormone actions.
What manifestations of endocrine problems in the older adult are commonly attributed to the aging process?
- A. Tremors and paresthesias
- B. Fatigue and mental impairment
- C. Hyperpigmentation and oily skin
- D. Fluid retention and hypertension
Correct Answer: B
Rationale: Fatigue and mental impairment are often attributed to normal aging but may indicate an underlying endocrine disorder such as hypothyroidism or adrenal insufficiency.
Insulin:
- A. stimulates the formation of glycogen.
- B. increases the transport of glucose into a cell.
- C. stimulates the synthesis of proteins and fats.
- D. all is applicable.
Correct Answer: D
Rationale: Certainly! The correct answer is D because insulin plays a crucial role in various metabolic processes. Firstly, insulin stimulates the formation of glycogen by promoting the uptake of glucose into the liver and muscles for storage. Secondly, it increases the transport of glucose into cells, regulating blood sugar levels. Lastly, insulin also stimulates the synthesis of proteins and fats by promoting the uptake of amino acids and fatty acids into cells. Therefore, all the statements in option D are correct based on the functions of insulin.
Growth hormone:
- A. is secreted by the adenohypophysis.
- B. stimulates growth of the musculoskeletal system.
- C. is also called somatotropic hormone.
- D. all is applicable.
Correct Answer: D
Rationale: Certainly! The correct answer is D because growth hormone is indeed secreted by the adenohypophysis, it stimulates growth of the musculoskeletal system, and it is also known as somatotropic hormone. All the statements in choices A, B, and C are true regarding growth hormone, making option D the correct choice. The other choices are incorrect because they do not encompass all the functions and characteristics of growth hormone as described in the question.