Fetal Development Questions Related

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Which immunoglobulin is the only one that crosses the placenta during pregnancy?

  • A. IgG
  • B. IgA
  • C. IgM
  • D. IgD
Correct Answer: A

Rationale: The correct answer is A: IgG. IgG is the only immunoglobulin that can cross the placenta due to its small size and ability to bind to the neonatal Fc receptor. This transfer provides passive immunity to the fetus, protecting it from infections. IgA primarily functions in mucosal immunity and is found in secretions like breast milk. IgM is too large to cross the placenta and is mainly produced in response to acute infections. IgD is primarily found on the surface of B cells and functions in the activation of these cells.