Nokea
Which immunoglobulins will initially protect a newborn baby of a breastfeeding mother (select all that apply)?
- A. IgA
- B. IgD
- C. IgE
- D. IgG
Correct Answer: A
Rationale: IgA is transferred through breast milk and provides mucosal immunity, while IgG crosses the placenta during pregnancy to provide systemic protection.
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During initial chemotherapy a patient with leukemia develops hyperkalemia and hyperuricemia. The nurse recognizes these symptoms as an oncologic emergency and anticipates that the priority treatment will be to
- A. increase urine output with hydration therapy
- B. establish electrocardiographic (ECG) monitoring
- C. administer a bisphosphonate such as pamidronate (Aredia)
- D. restrict fluids and administer hypertonic sodium chloride solution
Correct Answer: A
Rationale: Hydration therapy increases urine output, helping to excrete excess potassium and uric acid.
Recognize the following that would be classified as a delayed hypersensitivity reaction.
- A. Anaphylaxis
- B. Allergic contact dermatitis
- C. Cytotoxic hypersensitivity
- D. Immune complex hypersensitivity
Correct Answer: B
Rationale: The correct answer is B: Allergic contact dermatitis. This is classified as a delayed hypersensitivity reaction because it involves activation of T cells, which takes time to develop. Anaphylaxis (A) is an immediate hypersensitivity reaction mediated by IgE. Cytotoxic hypersensitivity (C) involves antibodies attacking cells directly, not delayed. Immune complex hypersensitivity (D) involves immune complexes depositing in tissues, triggering inflammation, not T cell activation.
What does the mechanism of chemotaxis accomplish?
- A. Causes the transformation of monocytes into macrophages
- B. Involves a pathway of chemical processes resulting in cellular lysis
- C. Attracts the accumulation of neutrophils and monocytes to an area of injury
- D. Slows the blood flow in a damaged area, allowing migration of leukocytes into tissue
Correct Answer: C
Rationale: Chemotaxis is the process by which immune cells such as neutrophils and monocytes are attracted to the site of injury or infection through chemical signals. These signals guide the cells to areas where they are needed most.
Which of the following statements is NOT true
- A. The highest prevalence of HIV infection is found in Sub-Saharan Africa
- B. Vaccines using attenuated HIV virus are in a "phase II" clinical trial
- C. During the clinical latency of HIV infection the counts of CD4+ lymphocytes are progressively diminishing
- D. During the final stages of the disease the viral RNA titer is high
Correct Answer: B
Rationale: The correct answer is B because vaccines using attenuated HIV virus are not in a "phase II" clinical trial. Attenuated virus vaccines are risky due to potential reversion to virulence. A: True, Sub-Saharan Africa has the highest HIV prevalence. C: CD4+ counts decline during clinical latency. D: Viral RNA titer increases in the final stages.
The type of immunological protection provided by plasma therapy is
- A. Natural active
- B. Natural passive
- C. Artificial active
- D. Artificial passive
Correct Answer: D
Rationale: The correct answer is D: Artificial passive. Plasma therapy involves administering preformed antibodies to provide immediate protection against a specific pathogen. This is considered artificial passive immunity because the antibodies are obtained from an external source rather than being produced by the individual's immune system.
Explanation:
1. Natural active immunity (Choice A) is when the body produces its antibodies after exposure to a pathogen, which is not the case in plasma therapy.
2. Natural passive immunity (Choice B) is when antibodies are passed from mother to fetus or through breast milk, not obtained through plasma therapy.
3. Artificial active immunity (Choice C) involves vaccination to stimulate the body's immune response, which is different from plasma therapy.
In summary, the correct answer is D (Artificial passive) because plasma therapy provides immediate immunity through externally sourced antibodies, distinguishing it from the other types of immunological protection.