Nokea
Which of the following antibiotics is contraindicated in patients with myasthenia gravis?
- A. Vancomycin
- B. Gentamicin
- C. Daptomycin
- D. Cephalexin
Correct Answer: B
Rationale: Gentamicin, an aminoglycoside, worsens neuromuscular blockade in myasthenia gravis, making it contraindicated.
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Only free drugs can act on target sites and can be eliminated.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: True; only free (unbound) drugs can interact with target sites and be filtered/excreted, as bound drugs are pharmacologically inactive.
Regular intake of small amount of ethanol may
- A. Increase HDL level and LDL oxidation
- B. Decrease HDL level and LDL oxidation
- C. Increase HDL level and decrease LDL oxidation
- D. Decrease synthesis of VLDL
Correct Answer: C
Rationale: Moderate ethanol intake is known to increase HDL (good cholesterol) levels and reduce LDL oxidation, offering some cardiovascular benefit.
Symptoms of folate deficiency include:
- A. Thinning of the hair
- B. Bruising easily
- C. Glossitis
- D. Numbness and tingling of the hands and feet
Correct Answer: C
Rationale: Glossitis (inflamed tongue) is a classic symptom of folate deficiency.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh between 60 kg and 75 kg.
- A. 450
- B. 476
- C. 480
- D. 490
Correct Answer: B
Rationale: Convert to z-scores: (60-70)/3 = -3.33, (75-70)/3 = 1.67. P(-3.33 < Z ≤ 1.67) = P(Z ≤ 1.67) - P(Z ≤ -3.33) = 0.9525 - (1 - 0.9996) = 0.9521. Then, 0.9521 * 500 ≈ 476, as per the document.
Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secretions. Each replacement drug has lipase, protease, and amylase components, but the drug is prescribed in units of:
- A. Lipase
- B. Protease
- C. Amylase
- D. Pancreatin
Correct Answer: A
Rationale: Pancreatic enzymes are dosed by lipase units, targeting fat malabsorption in cystic fibrosis.