Nokea
Varicella vaccine is recommended to be given to patients who are:
- A. HIV positive with a CD4+ T-lymphocyte percentage less than 15%
- B. Taking corticosteroids (up to 2 mg/kg/day or less than 20 mg/day)
- C. Pregnant
- D. Immunocompromised
Correct Answer: B
Rationale: Varicella vaccine is safe with low-dose steroids; HIV with low CD4 , pregnancy , or immunocompromise contraindicate it.
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Which of the following is a biguanides which is used for the treatment of diabetes mellitus type II:
- A. Repaglinide
- B. Glibenclamide
- C. Metformin
- D. Pioglitazone
Correct Answer: C
Rationale: Metformin is the primary biguanide used for type 2 diabetes, reducing hepatic glucose production and improving insulin sensitivity.
Patient education regarding prescribed medication includes:
- A. Instructions written at the high school reading level
- B. Discussion of expected adverse drug reactions
- C. How to store leftover medication such as antibiotics
- D. Verbal instructions always in English
Correct Answer: B
Rationale: Discussing adverse reactions is key to patient safety and adherence, unlike rigid reading levels , language limits , or leftover storage (C, less critical).
A nurse is providing instructions to the parent of an adolescent client who has a new prescription for Albuterol, PO. Which of the following instructions should the nurse include?
- A. You can take this medication to abort an acute asthma attack.
- B. Tremors are an adverse effect of this medication.
- C. Prolonged use of this medication can cause hyperglycemia.
- D. This medication can slow skeletal growth rate.
Correct Answer: B
Rationale: Tremors are a common side effect of albuterol due to beta-agonist stimulation.
A pharmacology student asks the instructor what an accurate description of a drug agonist is. What is the instructors best response?
- A. A drug that reacts with a receptor site on a cell preventing a reaction with another chemical on a different receptor site
- B. A drug that interferes with the enzyme systems that act as catalyst for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with some receptor sites preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
Inhaled corticosteroids in Bronchial Asthma:
- A. Produce modest immediate bronchodilation
- B. Are synergistic with inhaled methacholine
- C. Are antagonized by atropine
- D. Inhibit IgE-antigen binding
Correct Answer: D
Rationale: Inhaled corticosteroids reduce inflammation by inhibiting IgE-mediated responses.