Nokea
Which of the following is not a side effect of loop diuretics?
- A. Alkalosis
- B. Nausea
- C. Hypotension
- D. Potassium deficits
Correct Answer: B
Rationale: The correct answer is B: Nausea. Loop diuretics like furosemide work by inhibiting the reabsorption of sodium and water in the loop of Henle in the kidneys. This mechanism can lead to electrolyte imbalances, such as potassium deficits (choice D), and volume depletion, resulting in hypotension (choice C). Loop diuretics can also cause metabolic alkalosis (choice A) due to loss of hydrogen ions. Nausea, however, is not a common side effect of loop diuretics. Therefore, choice B is not a side effect of loop diuretics, making it the correct answer.
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Which of the following is not related to drug toxicity of Atenolol?
- A. CHF
- B. Tachycardia
- C. AV block
- D. Sedative appearance
Correct Answer: B
Rationale: The correct answer is B: Tachycardia. Atenolol is a beta-blocker that works by slowing down the heart rate, so tachycardia is not related to its toxicity. A: CHF can be exacerbated by Atenolol due to its negative inotropic effects. C: AV block can occur as Atenolol can further slow down the heart's conduction system. D: Sedative appearance can be a side effect of Atenolol due to its action on the central nervous system. In summary, tachycardia is not related to Atenolol toxicity because it decreases heart rate.
Which of the following drugs is associated with Stevens-Johnson syndrome?
- A. Valproic acid
- B. Quinidine
- C. Isoniazid
- D. Ethosuximide
Correct Answer: D
Rationale: Step 1: Ethosuximide is the correct answer as it is a known trigger for Stevens-Johnson syndrome due to its association with hypersensitivity reactions.
Step 2: Valproic acid can cause liver toxicity but is not typically linked to Stevens-Johnson syndrome.
Step 3: Quinidine is associated with drug-induced lupus but not commonly known to cause Stevens-Johnson syndrome.
Step 4: Isoniazid is linked to drug-induced hepatitis but not typically associated with Stevens-Johnson syndrome.
In summary, Ethosuximide is the correct choice due to its well-documented association with Stevens-Johnson syndrome, while the other options are linked to different adverse effects.
Which of the following is not a side effect associated with Prednisone toxicity?
- A. Cataracts
- B. Hypotension
- C. Psychosis
- D. Acne
Correct Answer: B
Rationale: The correct answer is B: Hypotension. Prednisone toxicity typically causes hypertension, not hypotension. Prednisone can lead to increased blood pressure due to its sodium-retaining effects. Cataracts (A), Psychosis (C), and Acne (D) are all known side effects of Prednisone toxicity. Cataracts can form due to long-term steroid use, psychosis can occur especially at higher doses, and acne is a common skin side effect. Therefore, hypotension is the odd one out among the choices given.
Which of the following is the antidote for lead poisoning?
- A. Naloxone
- B. Nitrite
- C. CaEDTA
- D. Dialysis
Correct Answer: C
Rationale: The correct answer is C: CaEDTA. Calcium disodium ethylenediaminetetraacetic acid (CaEDTA) is a chelating agent used to treat lead poisoning by binding to lead ions in the bloodstream and enhancing their excretion through urine. It forms stable complexes with lead, reducing its toxicity. Naloxone (A) is an opioid receptor antagonist, used to reverse opioid overdose. Nitrite (B) is used in cyanide poisoning. Dialysis (D) is not effective in removing lead from the body as lead is not effectively dialyzable.
Which of the following drugs is associated with extreme photosensitivity as a reaction?
- A. Digitalis
- B. Niacin
- C. Tetracycline
- D. Fluoroquinolones
Correct Answer: C
Rationale: The correct answer is C: Tetracycline. Tetracycline is associated with extreme photosensitivity due to its mechanism of action causing phototoxic reactions when exposed to sunlight. Digitalis (A) is a cardiac medication, niacin (B) is a B vitamin, and fluoroquinolones (D) are antibiotics, none of which are known to cause extreme photosensitivity reactions.