Nokea
Which of the following is NOT true of glucagon?
- A. produced by the pancreas
- B. increases blood glucose levels
- C. promotes the use of fat and protein instead of glucose
- D. stimulates the liver to store glucose as glycogen
Correct Answer: D
Rationale: The correct answer is D because glucagon actually stimulates the liver to release glucose into the bloodstream, not store glucose as glycogen. Glucagon helps increase blood glucose levels by promoting the breakdown of glycogen into glucose, and it also promotes the use of fat and protein for energy when glucose levels are low. Choices A, B, and C are all true statements about glucagon, making them incorrect options in this context.
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All of the following are hormones of the anterior pituitary except:
- A. Human growth hormone (GH).
- B. Follicle-stimulating hormone (FSH).
- C. Parathyroid hormone(PTH).
- D. Thyroid-stimulating hormone (TSH).
Correct Answer: C
Rationale: The correct answer is C: Parathyroid hormone (PTH). The anterior pituitary gland secretes hormones that regulate various bodily functions, such as growth, reproduction, and metabolism. PTH is actually produced by the parathyroid glands, not the anterior pituitary. Human growth hormone (GH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH) are all hormones secreted by the anterior pituitary gland. Therefore, C is the correct answer as it is not a hormone produced by the anterior pituitary gland.
Insulin:
- A. binds to GLUT 1-5 receptors in the peripheral tissues
- B. deficiency results in increased gluconeogenesis
- C. has a plasma half-life of 2-3 hours
- D. is secreted by the pancreatic A cells
Correct Answer: B
Rationale: The correct answer is B because insulin deficiency leads to increased gluconeogenesis due to the lack of inhibition on glucose production. Choice A is incorrect as insulin binds to GLUT 4 receptors, not GLUT 1-5. Choice C is wrong because insulin's half-life is only a few minutes. Choice D is also inaccurate as insulin is secreted by pancreatic beta cells, not A cells.
Which of the following would be associated with the action of steroids on cells?
- A. extracellular receptors with a specificity for only a single amino acid sequence on the hormone
- B. an enzyme that catalyzes the formation of cyclic AMP
- C. second-messenger systems
- D. a hormone-receptor complex that interacts directly with the cellʹs DNA
Correct Answer: D
Rationale: The correct answer is D because steroids act by binding to intracellular receptors, forming a hormone-receptor complex that directly interacts with the cell's DNA to regulate gene expression. This leads to changes in protein synthesis and cell function.
A: Extracellular receptors do not have specificity for a single amino acid sequence on the hormone. Steroids act intracellularly.
B: Formation of cyclic AMP is associated with G-protein coupled receptors, not steroid receptors.
C: Second-messenger systems are typically involved in signaling cascades triggered by extracellular ligands, not steroids.
The release of cortisol is stimulated by
- A. aldosterone
- B. angiotensin
- C. antidiuretic hormone (ADH)
- D. adrenocorticotropic hormone (ACTH)
Correct Answer: D
Rationale: The correct answer is D: adrenocorticotropic hormone (ACTH). ACTH is released by the pituitary gland in response to stress or low cortisol levels, stimulating the adrenal glands to release cortisol. Aldosterone (A) regulates electrolyte balance, angiotensin (B) regulates blood pressure, and antidiuretic hormone (C) regulates water balance, but they do not directly stimulate cortisol release. So, ACTH is the correct choice for stimulating cortisol production.
The nurse determines that a patient with a 2-hour OGTT of 152 mg/dL has
- A. diabetes
- B. impaired fasting glucose
- C. elevated A1C
- D. impaired glucose tolerance
Correct Answer: D
Rationale: A 2-hour OGTT result of 152 mg/dL indicates impaired glucose tolerance, which is a prediabetes state.