Which of the following is synthetic mineralocorticoids:
- A. Testosterone
- B. Estradiol
- C. Fludrocortisone
- D. Hydrocortisone
Correct Answer: C
Rationale: Fludrocortisone is a synthetic mineralocorticoid used to mimic aldosterone's effects on sodium retention.
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Not a prodrug
- A. Lisinopril
- B. Enalapril
- C. Ramipril
- D. Famotidine
Correct Answer: A
Rationale: Lisinopril is active; others are prodrugs.
All of following are examples of prodrugs except
- A. Levodopa
- B. Enlapril
- C. Omeprazole
- D. Indomethacin
Correct Answer: D
Rationale: Prodrugs (e.g., levodopa, enalapril, omeprazole) are inactive until metabolized. Indomethacin is active as administered.
Which action would the FDA take to expedite drug development and approval for an outbreak of smallpox?
- A. List smallpox as a health orphan disease
- B. Omit the preclinical research phase
- C. Extend the clinical research phase
- D. Fast track the investigational drug
Correct Answer: D
Rationale: Fast tracking prioritizes the drug within the FDA, expediting development for urgent needs like a smallpox outbreak. Orphan disease status, omitting preclinical phases, or extending clinical phases would not align with rapid response needs.
A nurse is planning caring for a client who is has a new prescription for Torsemide. The nurse should plan to monitor for which of the following adverse reactions of this medications? (Select one that does not apply.)
- A. Respiratory acidosis
- B. Hypokalemia
- C. Hypotension
- D. Ototoxicity
Correct Answer: A
Rationale: Torsemide can cause hypokalemia , hypotension , ototoxicity , and dysrhythmias , typical loop diuretic effects.
A nurse is monitoring a client who takes aspirin 81 mg PO daily. The nurse should identify which of the following manifestations as adverse effects of daily aspirin therapy? (Select one that does not apply.)
- A. Hypertension
- B. Coffee-ground emesis
- C. Tinnitus
- D. Nausea
Correct Answer: A
Rationale: Aspirin can cause GI bleeding , tinnitus , and nausea ; 'possessias' is likely a typo.