Nokea
Which of the following regarding E max is correct?
- A. E max assumes that as long as you increase the concentration of the drug, there will be a higher effect of the drug
- B. E max is used to compare the potency of different drugs
- C. E max assumes that all receptors are occupied by the drug and no increase in response is observed if a higher concentration of drug is obtained
- D. All of the previous points are incorrect
Correct Answer: C
Rationale: Emax is the maximal effect when all receptors are occupied; further dose increases yield no additional effect.
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Which of the following drugs has been shown to restore corticosteroid responsiveness for Bronchial Asthma:
- A. Salbutamol
- B. Sodium cromoglycate
- C. Zifirlukast
- D. Montelukast
Correct Answer: D
Rationale: Montelukast, a leukotriene inhibitor, enhances corticosteroid efficacy in asthma.
Which of the following beta-blockers also has additional alpha-blocking activity?
- A. Nadolol
- B. Pindolol
- C. Labetalol
- D. Esmolol
Correct Answer: C
Rationale: Labetalol has both beta and alpha-1 blocking activity, making it unique among beta-blockers.
A nurse is teaching a school-age child and his parents about a new prescription for Lisdexamfetamine. Which of the following information should the nurse include in the teaching? (Select one that does not apply.)
- A. An adverse effect of this medication is CNS stimulation.
- B. Administer the medication before bedtime.
- C. Monitor blood pressure while taking this medication.
- D. Increased dopamine leads to more activity
Correct Answer: B
Rationale: CNS stimulation , BP monitoring , and dopamine increase are key; it's taken in the morning, not bedtime.
Isotretinoin is prescribed for a client with severe acne. Before the administration of this medication, the nurse anticipates that which laboratory test will be prescribed?
- A. Platelet count
- B. Triglyceride level
- C. Complete blood count
- D. White blood cell count
Correct Answer: B
Rationale: Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be measured before treatment and periodically thereafter until the effect on the triglycerides has been evaluated. Options 1, 3, and 4 do not need to be monitored specifically during this treatment.
The U.S. Food and Drug Administration MedWatch system is activated when:
- A. There is an adverse event to a vaccine.
- B. The patient has a severe reaction that is noted in the 'Severe Reaction' section in the medication label.
- C. A lactating woman takes a medication that is potentially toxic to the breastfeeding infant.
- D. An adverse event or serious problem occurs with a medication that is not already identified on the label.
Correct Answer: D
Rationale: MedWatch reports new, unlabeled adverse events , beyond vaccines , known reactions , or lactation risks .