NCLEX Questions for Neurological System Related

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Which of the following statements about axon-guidance is TRUE?

  • A. Netrins are long-range cues for chemorepulsion
  • B. Semaphorins are short-range cues for chemorepulsion
  • C. Cadherins are short-range cues for contact attraction
  • D. Ephrins are short-range cues for contact attraction
Correct Answer: C

Rationale: Cadherins are cell adhesion molecules that mediate short-range contact attraction, guiding axons to their targets. Netrins, semaphorins, and ephrins also play roles in axon guidance, but they function through different mechanisms, such as long-range chemotaxis or repulsion. This diversity of guidance cues ensures precise navigation of growing axons.