Which of the following viruses has the name of the city where it was first discovered:
- A. Chikungunya virus
- B. Marburg virus
- C. Measles virus
- D. Epstein-Barr virus
Correct Answer: B
Rationale: Step-by-step rationale:
1. Marburg virus is named after the German city Marburg where it was first identified in 1967.
2. Chikungunya virus is named after a village in Tanzania.
3. Measles virus got its name from the Middle English word "maselen" meaning "many little spots".
4. Epstein-Barr virus is named after Michael Epstein and Yvonne Barr, who discovered it.
Summary:
B is correct as it is directly named after the city of its discovery. A, C, and D are incorrect as they are named after other locations, characteristics, or discoverers.
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While registering the child to the school Mantoux's test was made to define whether revaccination was needed test result is negative. What does this result of the test mean?
- A. Absence of antitoxic immunity to the tuberculosis
- B. Presence of antibodies for tubercle bacillus
- C. Absence of antibodies for tubercle bacillus
- D. Presence of cell immunity to the tuberculosis
Correct Answer: D
Rationale: Step 1: Mantoux test measures cell-mediated immunity response to tuberculosis.
Step 2: A negative result means no significant immune response to TB antigens.
Step 3: Option A is incorrect, as it refers to antitoxic immunity, not cell immunity.
Step 4: Option B is incorrect, as it mentions antibodies, not cell-mediated immunity.
Step 5: Option C is incorrect, as it states absence of antibodies, not cell immunity.
Step 6: Option D is correct as it directly correlates with the purpose of Mantoux test.
The following viruses are referred to the Filoviridae family
- A. Lassa virus and lymphocytic choriomeningitis viruses
- B. Chikungunya virus and Sindbis virus
- C. Marburg virus and Ebola virus
- D. Crimean-Congo virus and Hantaan virus
Correct Answer: C
Rationale: The correct answer is C because Marburg virus and Ebola virus belong to the Filoviridae family. These viruses are characterized by their filamentous shape and are known to cause severe hemorrhagic fever in humans. Both viruses have caused outbreaks with high mortality rates.
Choice A (Lassa virus and lymphocytic choriomeningitis viruses) are not part of the Filoviridae family. They belong to the Arenaviridae family, which also includes viruses that cause hemorrhagic fevers.
Choice B (Chikungunya virus and Sindbis virus) are arboviruses belonging to the Togaviridae family, which are not related to the Filoviridae family.
Choice D (Crimean-Congo virus and Hantaan virus) are part of the Nairoviridae and Hantaviridae families, respectively, and not the Filoviridae family.
The net gain of ATP molecules after the breakdown of one glucose molecule in glycolysis is
- A. 1
- B. 2
- C. 3
- D. 4
Correct Answer: B
Rationale: The correct answer is B (2). During glycolysis, one glucose molecule is broken down into two molecules of pyruvate. In this process, a net gain of 2 ATP molecules is produced through substrate-level phosphorylation. Specifically, ATP is generated during the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate and during the conversion of phosphoenolpyruvate to pyruvate. The other choices are incorrect because the net gain of ATP molecules in glycolysis is not 1, 3, or 4; it is 2 based on the specific enzymatic reactions involved in the pathway.
The sample used to proving epidemic meningitis is:
- A. CSF transported at 37°C (CSF sample, blood, nasopharyngeal secretion)
- B. Feces
- C. CSF transported at +4°C
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A because CSF (Cerebrospinal fluid) is the sample used for proving epidemic meningitis. It should be transported at 37°C to maintain its integrity. Blood and nasopharyngeal secretions are not typically used for diagnosing meningitis. Choice B, feces, is unrelated to the diagnosis of meningitis. Choice C, CSF transported at +4°C, is incorrect as it should be transported at 37°C to prevent degradation of the sample. Therefore, A is the correct choice for proving epidemic meningitis due to the specificity of the sample and the proper transport conditions.
Which bacteria are responsible for causing bacterial meningitis?
- A. Neisseria meningitidis
- B. Haemophilus influenzae
- C. Streptococcus pneumoniae
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D, "All of the above." Bacterial meningitis can be caused by Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae. These bacteria are common pathogens associated with meningitis. Each of them can lead to serious infections in the brain and spinal cord. Neisseria meningitidis is known for causing meningococcal meningitis, Haemophilus influenzae is a common cause of H. influenzae meningitis, and Streptococcus pneumoniae is responsible for pneumococcal meningitis. Therefore, since all three bacteria can cause bacterial meningitis, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually can cause bacterial meningitis; it is not limited to just one specific type.