Basic Immune System Quizlet Related

Review Basic Immune System Quizlet related questions and content

Which of the following statements is most correct? Immunoglobulin gene rearrangement:

  • A. Occurs after transcription of an immunoglobulin gene
  • B. Creates a complete V exon in the germline DNA
  • C. Creates a complete V exon in the B cell DNA
  • D. Both A and B are correct
Correct Answer: C

Rationale: The correct answer is C because immunoglobulin gene rearrangement creates a complete V exon in the B cell DNA. This process happens during B cell development, where segments of V, D, and J gene regions are rearranged to form a functional immunoglobulin gene. This rearrangement occurs before transcription, so option A is incorrect. Option B is incorrect because the V exon is not complete in the germline DNA, but rather created through rearrangement in the B cell DNA. Option D is incorrect as it combines two incorrect statements.