A nurse is caring for a patient who is supposed to receive two drugs at the same time. What is the nurse's priority action?
- A. Wash her hands before handling the medications.
- B. Consult a drug guide for compatibility.
- C. Question the patient concerning drug allergies.
- D. Identify the patient by checking the armband and asking the patient to state his name.
Correct Answer: B
Rationale: A nurse should first consult a drug guide for compatibility when two or more drugs are being given at the same time. After compatibility is determined the medication can be administered. The nurse will perform hand hygiene, check for patient allergies, and ensure the right patient receives the medication by using two identifiers.
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The nurse receives an order to administer an unfamiliar medication and obtains a nurse's drug guide published four years earlier. What is the nurse's most prudent action?
- A. Find a more recent reference source.
- B. Use the guide if the drug is listed.
- C. Ask another nurse for drug information.
- D. Verify the information in the guide with the pharmacist.
Correct Answer: A
Rationale: The nurse is responsible for all medications administered and must find a recent reference source to ensure the information learned about the medication is correct and current. Using an older drug guide could be dangerous because it would not contain the most up-to-date information. Asking another nurse or the pharmacist does not guarantee accurate information will be obtained and could harm the patient if the information is wrong.
Prior to prescribing metformin, the provider should:
- A. Draw a serum creatinine to assess renal function
- B. Try the patient on insulin
- C. Tell the patient to increase iodine intake
- D. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
Correct Answer: A
Rationale: Metformin requires renal function assessment (creatinine) due to lactic acidosis risk; insulin isn't a prerequisite.
Enterohepatic circulation is seen in
- A. Ampicillin
- B. Benzylpenicillin
- C. Norfloxacin
- D. Streptomycin
Correct Answer: D
Rationale: Streptomycin is excreted via bile and reabsorbed, unlike the others.
A 44-year-old woman with systemic lupus erythematosus presents to her primary care physician for follow-up. She is currently being managed with an oral glucocorticoid agent. The most likely mechanism of action of this medication involves which of the following?
- A. Inhibition of erythrocytes
- B. Inhibition of macrophages
- C. Stimulation of cyclooxygenase 2 synthesis
- D. Stimulation of phospholipase A2
Correct Answer: B
Rationale: Glucocorticoids inhibit macrophages and other immune cells, reducing inflammation in conditions like lupus.
The anthelminthic whose dose is 400 gms stat for most worm infestation:
- A. Piperazine
- B. Mebendazole
- C. Albendazole
- D. Levamisole
Correct Answer: C
Rationale: Albendazole is commonly prescribed as a single 400 mg dose (stat) for most intestinal worm infestations, such as ascariasis and hookworm, due to its broad-spectrum efficacy.