Nokea
A patient for whom antiretroviral therapy has been prescribed informs the nurse that she is taking oral contraceptives. The nurse responds that the combination of oral contraceptives and antiretroviral therapy can lead to which of the following?
- A. Decreased effectiveness of antiviral therapy.
- B. Increased risk of vaginal bleeding
- C. Decreased effectiveness of birth control pills
- D. Increased serum level of the antiretroviral
- E. Increased risk of infection
Correct Answer: C
Rationale: Antiretrovirals decrease the effectiveness of oral birth control agents. Combining antiretrovirals with birth control pills does not, however, increase the risk of vaginal bleeding, increase serum levels of the antiretroviral, decrease the effectiveness of antiviral therapy, or increase the risk of infection.
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An HIV-positive patient on antiretroviral therapy informs the nurse that he is considering taking sildenafil. The nurse informs the patient that he may experience which of the following when taking sildenafil with antiretroviral therapy?
- A. Feching of dizziness
- B. Tching of skin
- C. Risk of hypotension
- D. Depression
- E. Nausea
Correct Answer: C
Rationale: The nurse should educate the patient regarding the associated risks, such as hypotension, visual disturbances, and prolonged penile erection. Feeling of dizziness, itching of skin, depression, and nausea are not conditions that are specifically associated with sildenafil and antiretroviral drugs.
A nurse is providing care to a client receiving highly active antiretroviral therapy (HAART). The nurse would expect the client to receive which of the following antiretroviral agents? Select all that apply.
- A. Protease inhibitors
- B. Reverse transcriptase inhibitors
- C. Nonnucleoside reverse transcriptase inhibitors
- D. Entry inhibitors
- E. Integrase inhibitors
Correct Answer: A,B,C
Rationale: HAART includes three categories of antiretroviral drugs: protease inhibitors, reverse transcriptase inhibitors, and nonnucleoside reverse transcriptase inhibitors.
After teaching a group of nursing students about antiretroviral drugs, the instructor determines that the teaching was successful when the students identify that these drugs are used to treat which infections? Select all that apply.
- A. Hepatitis C virus (HCV)
- B. Human immunodeficiency virus (HIV)
- C. Acquired immunodeficiency syndrome (AIDS)
- D. Herpes simplex virus (HSV) 1
- E. Herpes simplex virus (HSV) 2
Correct Answer: B,C
Rationale: Antiretroviral drugs are used to treat HIV and AIDS.
A patient is being treated with saquinavir. The nurse would assess the patient for which of the following?
- A. Increase in patient's weight
- B. Evidence of liver dysfunction
- C. Photosensitivity
- D. Allergic skin reaction
- E. Diarrhea
Correct Answer: A
Rationale: Patients taking saquinavir experience redistribution of body fat, with the movement to the center of the body. The nurse should spend time with these patients, encouraging them to verbalize their feelings regarding this change in appearance. Taking saquinavir does not cause liver dysfunction, photosensitivity, allergic skin reactions, or diarrhea.
A patient is being discharged from a health care facility but is required to continue antiviral therapy at home. Which of the following points should the nurse include in the teaching plan to educate the patient?
- A. A slight elevation in temperature is normal and needn't be reported.
- B. Double the dosage of the drug if you miss a dose.
- C. Stop taking the drug as soon as the symptoms of the infection disappear.
- D. Make sure to notify your primary health care provider if you develop any adverse reactions.
- E. Take the drug with food to reduce stomach upset
Correct Answer: D
Rationale: The nurse should instruct the patient to report adverse reactions to the primary health care provider. The nurse should also tell the patient to report any increase in temperature, even if it is a slight increase. If the patient misses a dose, the next dose should be taken as soon as remembered, but it should not be doubled. The nurse should also instruct the patient to take the drug exactly as directed for the full course of therapy, even if the symptoms of the infection disappear. Taking the drug with food is not a general requirement for all antivirals but may apply to specific drugs.