A patient with diabetes is learning to mix regular insulin and NPH insulin in the same syringe. The nurse determines that additional teaching is needed when the patient does what?
- A. Withdraws the NPH dose into the syringe first
- B. Injects air equal to the NPH dose into the NPH vial first
- C. Removes any air bubbles after withdrawing the first insulin
- D. Adds air equal to the insulin dose into the regular vial and withdraws the dose
Correct Answer: A
Rationale: When mixing insulin, the correct order is to draw up the regular insulin first, followed by NPH insulin.
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Which is not Na+ dependent for absorption?
- A. thiamin
- B. riboflavin
- C. niacin
- D. folate
Correct Answer: D
Rationale: The correct answer is D: folate. Folate absorption is not Na+ dependent as it is primarily absorbed in the small intestine through a carrier-mediated process that is independent of sodium. Thiamin, riboflavin, and niacin absorption, on the other hand, are Na+ dependent processes that rely on sodium co-transporters for uptake in the small intestine. Thiamin is absorbed through a sodium-dependent active transport system, riboflavin requires a sodium-dependent carrier protein for absorption, and niacin absorption involves a sodium-dependent transporter in the small intestine. Therefore, folate is the only option that is not Na+ dependent for absorption.
What is the mass of hydrogen chloride that reacts with 5.1 g of ammonia?
- A. 3.65g
- B. 10.95g
- C. 7.05g
- D. 21.15g
Correct Answer: B
Rationale: To find the mass of hydrogen chloride that reacts with 5.1g of ammonia, we need to use the stoichiometry of the balanced chemical equation. The balanced equation for the reaction between ammonia (NH3) and hydrogen chloride (HCl) is:
NH3 + HCl → NH4Cl
From the equation, we can see that 1 mole of NH3 reacts with 1 mole of HCl to form 1 mole of NH4Cl. Therefore, the molar ratio of NH3 to HCl is 1:1.
First, we need to convert the given mass of ammonia (5.1g) to moles using the molar mass of ammonia (17g/mol):
5.1g NH3 * (1 mol NH3 / 17g NH3) = 0.3 mol NH3
Since the molar ratio of NH3 to HCl is 1:1, the moles of HCl that react with
T3 and T4:
- A. stimulate the adenohypophysis to secrete TSH.
- B. regulate the basal metabolic rate (BMR).
- C. stimulate osteoclastic activity, thereby elevating plasma calcium levels.
- D. all is applicable.
Correct Answer: B
Rationale: Step-by-step rationale for why choice B is correct:
1. T3 and T4 are thyroid hormones produced by the thyroid gland.
2. These hormones play a crucial role in regulating the body's metabolism.
3. T3 and T4 directly influence the basal metabolic rate (BMR).
4. An increase in T3 and T4 levels leads to an increase in BMR.
5. Therefore, choice B is correct as T3 and T4 regulate the basal metabolic rate.
Summary of why other choices are incorrect:
- Choice A (stimulate the adenohypophysis to secrete TSH) is incorrect as TSH is produced by the pituitary gland, not affected by T3 and T4.
- Choice C (stimulate osteoclastic activity, thereby elevating plasma calcium levels) is incorrect as this function is primarily attributed to parathyroid hormone, not T3 and T4.
- Choice D (all is applicable) is incorrect as only choice B
A 33-year-old woman becomes poisoned after receiving an injection of concentrated botulinum toxin. Which of the following is the main neurochemical mechanism by which this Clostridium toxin causes its effects?
- A. Directly activates all muscarinic and nicotinic receptors
- B. Inhibits ACh release from all cholinergic nerves
- C. Prevents neuronal norepinephrine reuptake
- D. Releases norepinephrine via a nonexocytotic process
Correct Answer: B
Rationale: The correct answer is B: Inhibits ACh release from all cholinergic nerves. Botulinum toxin blocks the release of acetylcholine (ACh) from cholinergic nerve terminals, leading to muscle paralysis. This occurs through the cleavage of SNARE proteins, preventing vesicle fusion and neurotransmitter release. Choice A is incorrect because botulinum toxin does not directly activate receptors. Choice C is incorrect as botulinum toxin does not affect neuronal norepinephrine reuptake. Choice D is incorrect because botulinum toxin does not release norepinephrine via a nonexocytotic process.
Terbutaline specifically stimulates:
- A. Alpha1 receptors
- B. Alpha2 receptors
- C. Beta1 receptors
- D. Beta2 receptors
Correct Answer: D
Rationale: Terbutaline specifically stimulates Beta2 receptors. This leads to bronchodilation by relaxing smooth muscles in the airways. Beta2 receptors are predominantly found in the lungs. Option A and B are incorrect as terbutaline does not target Alpha receptors. Option C is incorrect as terbutaline does not primarily stimulate Beta1 receptors, which are mainly found in the heart.