Nokea
All of the following reduces intensity of first heart sound (S1) except
- A. Mechanical ventilation
- B. Calcific mitral stenosis
- C. Short PR interval
- D. LV dysfunction
Correct Answer: B
Rationale: Calcific mitral stenosis typically increases the intensity of the first heart sound (S1).
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The reason that the hematocrit is so high is
- A. chronic hypoxia
- B. it was taken in a low cardiac output state
- C. it was a peripheral finger stick
- D. embolic stroke
Correct Answer: A
Rationale: Chronic hypoxia leads to secondary polycythemia as a compensatory mechanism.
Insulin-like growth factor-l (IGF-I):
- A. Increases during pubertal growth spurt
- B. Is a single polypeptide chain
- C. Is produced in pancreas
- D. Is secreted in a pulsatile manner
Correct Answer: A
Rationale: IGF-I levels rise significantly during the pubertal growth spurt, contributing to rapid growth and development.
In embryology:
- A. Most defects occur with teratogens in the first 2 weeks post-conception
- B. The urachus becomes the median umbilical ligament
- C. The mesonephric duct becomes the male organs
- D. The thyroid develops from the floor of the primitive larynx
Correct Answer: B
Rationale: The urachus becomes the median umbilical ligament. Most defects occur after the first 2 weeks, and the thyroid develops from the floor of the pharynx.
Congenital heart disease causing cyanosis without respiratory distress include EXCEPT
- A. tricuspid atresia
- B. aortic stenosis
- C. Ebstein anomaly
- D. pulmonary atresia
Correct Answer: B
Rationale: Tricuspid atresia, Ebstein anomaly, and pulmonary atresia can cause cyanosis without respiratory distress, while aortic stenosis typically does not.
In statistical methodology:
- A. The median and mean are different when the population distribution is skewed
- B. Mode refers to the value that occurs with the highest frequency
- C. The value of 'r' (coefficient of variation) ranges from -1 to +1
- D. Incidence is defined as the number of cases seen in the population at any given period of time
Correct Answer: A
Rationale: The median and mean differ in skewed distributions because the mean is influenced by extreme values, while the median is not.