During discharge teaching for the patient with Addison's disease, which statement by the patient indicates that the nurse needs to do additional teaching?
- A. I should always call the doctor if I develop vomiting or diarrhea.
- B. If my weight goes down, my dosage of steroid is probably too high.
- C. I should double or triple my steroid dose if I undergo rigorous physical exercise.
- D. I need to carry an emergency kit with injectable hydrocortisone in case I can't take my medication by mouth.
Correct Answer: B
Rationale: A decrease in weight does not typically indicate that steroid dosage is too high; the patient should understand how to adjust steroids for illness, stress, or physical activity.
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Which hormone is most important in insulin secretion?
- A. gastrin
- B. CCK
- C. GIP
- D. secretin
Correct Answer: C
Rationale: The correct answer is C: GIP. GIP, or glucose-dependent insulinotropic peptide, is the most important hormone in insulin secretion. It is released by the intestines in response to glucose intake, stimulating the release of insulin from the pancreas. Gastrin (A) is involved in gastric acid secretion, not insulin. CCK (B) and secretin (D) are involved in digestion and pancreatic enzyme secretion, not insulin regulation. So, GIP is the correct answer as it directly stimulates insulin release in response to glucose levels.
Eicosanoids are not true hormones because they __________.
- A. they act locally, not on distal organs as do true hormones
- B. don't have target organs
- C. mediate inflammatory reactions
- D. are lipid in nature
Correct Answer: A
Rationale: The correct answer is A. Eicosanoids are not true hormones because they act locally, not on distal organs like true hormones. Eicosanoids are produced and released in response to specific stimuli at the site of action, affecting nearby cells. This local action distinguishes them from true hormones, which are produced in one part of the body and travel through the bloodstream to distant target organs to elicit a response. Choices B, C, and D are incorrect because eicosanoids do have target organs (B), mediate inflammatory reactions (C), and are lipid in nature (D), but these characteristics do not define them as hormones.
A 35-year-old female presents to your office for a regular check-up. Her only complaint is recurrent migraine headaches, which have increased in frequency over the years. On examination, her blood pressure is elevated at 150/70. You decide to start her on antihypertensive therapy that is also used for prophylaxis of migraines. Which medication is it?
- A. Clonidine
- B. Prazosin
- C. Hydrochlorothiazide
- D. Propranolol
Correct Answer: D
Rationale: The correct answer is D: Propranolol. Propranolol is a beta-blocker that is commonly used for migraine prophylaxis. It helps reduce the frequency and severity of migraines by blocking the action of adrenaline on blood vessels in the brain. In this case, the patient has elevated blood pressure and migraines, so starting her on propranolol can address both issues effectively.
Choice A: Clonidine is an alpha-2 agonist used for hypertension, but it is not commonly used for migraine prophylaxis.
Choice B: Prazosin is an alpha-1 blocker primarily used for the treatment of hypertension, but it is not typically used for migraine prophylaxis.
Choice C: Hydrochlorothiazide is a diuretic used for hypertension by reducing blood volume, but it is not effective for migraine prophylaxis.
In summary, propranolol is the most appropriate choice as it addresses both the elevated blood pressure and the recurrent
Mole for mole, which of the following has the greatest effect on plasma osmolality?
- A. Progesterone
- B. Cortisol
- C. Vasopressin
- D. Aldosterone
Correct Answer: C
Rationale: Plasma osmolality is primarily regulated by the concentration of solutes in the blood. Vasopressin, also known as antidiuretic hormone (ADH), plays a key role in regulating water reabsorption in the kidneys, thus affecting plasma osmolality. When plasma osmolality increases, vasopressin is released to increase water reabsorption, leading to a decrease in plasma osmolality. Progesterone, cortisol, and aldosterone do not directly influence water reabsorption and therefore do not have as significant an impact on plasma osmolality as vasopressin.
Insulin:
- A. stimulates the formation of glycogen.
- B. increases the transport of glucose into a cell.
- C. stimulates the synthesis of proteins and fats.
- D. all is applicable.
Correct Answer: D
Rationale: Certainly! The correct answer is D because insulin plays a crucial role in various metabolic processes. Firstly, insulin stimulates the formation of glycogen by promoting the uptake of glucose into the liver and muscles for storage. Secondly, it increases the transport of glucose into cells, regulating blood sugar levels. Lastly, insulin also stimulates the synthesis of proteins and fats by promoting the uptake of amino acids and fatty acids into cells. Therefore, all the statements in option D are correct based on the functions of insulin.