Glibenclamide and chlorpropamide:
- A. Are well absorbed in Gl tract
- B. Increase release of endogenic insulin by pancreatic beta cells
- C. Is used as hormone replacement therapy for diabetes mellitus
- D. Is for internal use only
Correct Answer: B
Rationale: Glibenclamide and chlorpropamide increase endogenous insulin release from beta cells.
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A nurse is providing information to a client who has a new prescription for Hydrochlorothiazide. Which of the following information should the nurse include?
- A. Take the medication with food.
- B. Plan to take the medication at bedtime.
- C. Expect increased swelling of the ankles.
- D. Fluid intake should be limited in the morning.
Correct Answer: A
Rationale: Taking with food reduces GI upset, a standard instruction for hydrochlorothiazide.
A patient is diagnosed with histoplasmosis and will begin taking ketoconazole. What information will the nurse include when teaching this patient about this medication?
- A. Take the medicine twice daily
- B. Take the medication with food
- C. You may consume small amounts of alcohol
- D. You will not need lab tests while taking this drug
Correct Answer: B
Rationale: Ketoconazole absorption improves with food; it's once daily, and alcohol or no labs are incorrect. Ketoconazole should be taken with food.
Dwayne has recently started on carbamazepine to treat seizures. He comes to see you and you note that while his carbamazepine levels had been in the therapeutic range, they are now low. The possible cause for the low carbamazepine levels include:
- A. Dwayne hasn't been taking his carbamazepine because it causes insomnia.
- B. Carbamazepine auto-induces metabolism, leading to lower levels in spite of good compliance.
- C. Dwayne was not originally prescribed the correct amount of carbamazepine.
- D. Carbamazepine is probably not the right antiseizure medication for Dwayne.
Correct Answer: B
Rationale: Carbamazepine induces its own metabolism (auto-induction), reducing levels over time.
A nurse is administering digoxin to a patient. To administer medications so that the drug is as effective as possible, the nurse needs to consider what?
- A. Peak plasma level
- B. Half-life
- C. Drug interactions
- D. Timing of administration
Correct Answer: D
Rationale: To maximize digoxin's effectiveness, the nurse must consider timing of administration to align with therapeutic levels and avoid toxicity, especially given its narrow therapeutic index. Peak plasma level, half-life, and drug interactions are factors, but timing is critical for efficacy.
Which action will the nurse take when it is determined that the narcotic count is incorrect while obtaining a medication from the narcotic area?
- A. Determine the cause of the discrepancy at the end of the shift.
- B. Notify the health care provider stat.
- C. Call the nurse from the previous shift to determine if there was a discrepancy earlier.
- D. Report the discrepancy to the charge nurse immediately.
Correct Answer: D
Rationale: Reporting the discrepancy to the charge nurse immediately enables the supervisory staff to narrow the time frame during which a medication was taken and not documented. The discrepancy needs to be addressed immediately, and therefore determining the cause of the discrepancy at the end of the shift is not the most appropriate action for the nurse to take. It is not appropriate to contact the health care provider for an incorrect narcotic count. The count would have been verified at shift change; calling the nurse from the previous shift is not an appropriate action for the nurse to take.