Granulomatosis infantiseptica is caused by:
- A. Staphylococcus aureus
- B. Mycobacterium tuberculosis
- C. Listeria monocytogenes
- D. All of the above
Correct Answer: C
Rationale: Granulomatosis infantiseptica is commonly caused by Listeria monocytogenes, a bacterium known to infect newborns. It can lead to granulomatous lesions in various organs. Staphylococcus aureus and Mycobacterium tuberculosis are not typical causes of this condition in infants. Choice D is incorrect as it suggests all listed bacteria are responsible, which is not accurate. Therefore, the correct answer is C as Listeria monocytogenes is the specific pathogen associated with granulomatosis infantiseptica.
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Bacteria that thrive in high salt concentrations are called:
- A. acidophiles
- B. thermophiles
- C. halophiles
- D. mesophiles
Correct Answer: C
Rationale: The correct answer is C: halophiles. Halophiles are bacteria that thrive in high salt concentrations due to their ability to regulate osmotic pressure. They have adapted mechanisms to survive in such extreme environments. Option A, acidophiles, thrive in acidic conditions, not high salt concentrations. Option B, thermophiles, thrive in high temperature environments. Option D, mesophiles, thrive in moderate temperature conditions, not necessarily high salt concentrations. Therefore, the correct choice is C as it specifically refers to bacteria that thrive in high salt concentrations.
In the morning a patient had nausea, abdominal discomfort, single vomiting, dry mouth. In the evening, the patient presented with the increasing general weakness, double vision, difficult swallowing of solid food. Objectively: ptosis, mydriasis, anisocoria, absence of gag and pharyngeal reflex, dry mucous membranes. The previous evening the patient had dinner with canned food and alcohol. What is the presumptive diagnosis?
- A. Botulism
- B. Poliomyelitis
- C. Food toxicoinfection
- D. Acute ischemic stroke
Correct Answer: A
Rationale: The correct answer is A: Botulism. The symptoms described, such as ptosis, mydriasis, anisocoria, dry mouth, and absent gag reflex, are classic signs of botulism. Botulism is caused by the bacterium Clostridium botulinum, commonly found in improperly preserved canned foods. The progression from gastrointestinal symptoms to neurological symptoms, like double vision and difficulty swallowing, is characteristic of botulism due to the toxin's effect on neuromuscular transmission. Poliomyelitis primarily affects the motor neurons and presents with different symptoms. Food toxicoinfection typically involves gastrointestinal symptoms and does not manifest with the neurological findings seen in this case. Acute ischemic stroke presents with sudden onset neurological deficits due to impaired blood flow to the brain, which is not consistent with the gradual progression of symptoms in this scenario.
In which of the following disease, the respiratory tract is infected:
- A. Tuberculosis
- B. Q-fever
- C. Legionnaires disease
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above. Tuberculosis, Q-fever, and Legionnaires disease all can infect the respiratory tract. Tuberculosis is a bacterial infection affecting the lungs, Q-fever is caused by a bacterium that primarily affects the lungs, and Legionnaires disease is a severe form of pneumonia. All three diseases specifically target the respiratory system, making them the correct choices. Choices A, B, and C are incorrect because each of them individually infects the respiratory tract, not just one or two of them.
A Gram-negative, comma-shaped bacterium was isolated from a patient with cholera. What is the most likely causative agent?
- A. Vibrio cholerae
- B. Shigella dysenteriae
- C. Salmonella typhi
- D. Campylobacter jejuni
Correct Answer: A
Rationale: The correct answer is A: Vibrio cholerae. This is because Vibrio cholerae is a Gram-negative, comma-shaped bacterium known to cause cholera. The characteristic shape and the association with cholera make it the most likely causative agent in this case.
Explanation for incorrect choices:
B: Shigella dysenteriae - Shigella dysenteriae is a Gram-negative bacterium that causes bacillary dysentery, not cholera.
C: Salmonella typhi - Salmonella typhi is a Gram-negative bacterium that causes typhoid fever, not cholera.
D: Campylobacter jejuni - Campylobacter jejuni is a Gram-negative bacterium that commonly causes foodborne gastroenteritis, not cholera.
A 35-year-old patient with a severe respiratory infection had sputum that showed Gram-negative, comma-shaped bacteria. What is the likely causative agent?
- A. Vibrio cholerae
- B. Shigella dysenteriae
- C. Campylobacter jejuni
- D. Helicobacter pylori
Correct Answer: C
Rationale: The correct answer is C: Campylobacter jejuni. This bacterium is Gram-negative and comma-shaped, commonly causing respiratory infections. Vibrio cholerae (A) causes cholera, not respiratory infections. Shigella dysenteriae (B) causes dysentery, not respiratory infections. Helicobacter pylori (D) is associated with gastric ulcers, not respiratory infections. Therefore, Campylobacter jejuni is the most likely causative agent based on the given information.