It is customary to administer systemic corticosteroids early in the morning because:
- A. This prevents early morning bronchospasms
- B. To inhibit adrenocorticotrophic hormone over secretion
- C. To achieve high plasma concentrations throughout the day
- D. To prevent adrenocortex suppression
Correct Answer: D
Rationale: Morning dosing aligns with cortisol peaks, minimizing adrenal suppression.
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Which of the following drugs is used to accelerate pulmonary maturation in the fetus in women with premature labor?
- A. Aminoglutethimide
- B. Betamethasone
- C. Mifepristone
- D. Misoprostol
Correct Answer: B
Rationale: Betamethasone, a glucocorticoid, is administered to enhance fetal lung maturation by stimulating surfactant production in preterm labor.
A nurse is providing teaching for a client who is withdrawing from alcohol and has a new prescription for Propranolol. Which of the following information should the nurse to include in the teaching?
- A. Increases the risk for seizure activity
- B. Provides a form of aversion therapy
- C. Decreases cravings
- D. Results in mild hypertension
Correct Answer: C
Rationale: Propranolol reduces withdrawal symptoms like tremors and cravings , not seizures or aversion.
Decision support systems often provide medication alerts that tell the prescriber:
- A. Patient history data with a summary of their diagnoses
- B. The usual dosage for the drug being prescribed
- C. The patient's latest laboratory values, such as potassium levels
- D. Potential drug-to-drug interactions with other medications the patient is taking
Correct Answer: D
Rationale: Decision support systems primarily alert prescribers to drug-drug interactions.
The nurse promotes optimal drug effectiveness by doing what? (Select one that does not apply.)
- A. Incorporate basic history and physical assessment factors into the plan of care.
- B. Evaluate the effectiveness of drugs after they have been administered.
- C. Modify the drug regimen to modify adverse or intolerable effects.
- D. Minimize the number of medications administered to patients.
Correct Answer: D
Rationale: Incorporate basic history and physical assessment factors into any plan of care so that obvious problems can be identified and handled promptly. If a drug simply does not do what it is expected to do, further examine the factors that are known to influence drug effects. Frequently, the drug regimen can be modified to deal with that influence. Minimizing the number of medications administered is usually not an option because each drug is ordered for a reason of necessity for the patient.
Candesartan and irbesartan are angiotensin receptor blockers that are used to treat hypertension. The therapeutic dose range for candesartan is 4 to 32 mg, as compared to 75 to 300 mg for irbesartan. which of the following regarding this statement is correct?
- A. Candesartan is more potent than is irbesartan
- B. Candesartan and irbesartan have different efficacy
- C. Candesartan is a non competitive antagonist for irbesartan
- D. Irbesartan is a competitive antagonist for candesartan
Correct Answer: A
Rationale: Lower dose range for candesartan indicates higher potency (lower EC50) compared to irbesartan.