Endocrine System Multiple Choice Questions Related

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Mole for mole, which of the following has the greatest effect on plasma osmolality?

  • A. Progesterone
  • B. Cortisol
  • C. Vasopressin
  • D. Aldosterone
Correct Answer: C

Rationale: Plasma osmolality is primarily regulated by the concentration of solutes in the blood. Vasopressin, also known as antidiuretic hormone (ADH), plays a key role in regulating water reabsorption in the kidneys, thus affecting plasma osmolality. When plasma osmolality increases, vasopressin is released to increase water reabsorption, leading to a decrease in plasma osmolality. Progesterone, cortisol, and aldosterone do not directly influence water reabsorption and therefore do not have as significant an impact on plasma osmolality as vasopressin.