Nokea
Rho immune globulin (RhoGAM) is given to:
- A. Infants born to women who are Rh positive
- B. Sexual partners of Rh-positive women
- C. Rh-negative women after a birth, miscarriage, or abortion
- D. Rh-negative women at 36 weeks gestation
Correct Answer: C
Rationale: RhoGAM prevents Rh sensitization in Rh-negative women post-delivery; it's not for infants , partners , or late gestation alone.
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The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
B-Blockers are contra indicated in
- A. Hypertension
- B. Congestive cardiac failure
- C. Anxiety states
- D. Hyperthyroidis m
Correct Answer: B
Rationale: Beta-blockers worsen congestive heart failure.
Plasma concentration of drug at time 0 is 96(g/ml). If t½ is 2 hours concentration in plasma at 10 hours will be
- A. 48
- B. 24
- C. 12
- D. 3
Correct Answer: D
Rationale: In first-order kinetics, the concentration halves every half-life (t½ = 2 hours). At 10 hours (5 half-lives), 96 → 48 → 24 → 12 → 6 → 3 µg/ml.
A nurse is assessing a pregnant client and learns that the client is addicted to cocaine. The nurse informs the client about the risks of cocaine addiction for her fetus. Which of the following would the nurse include?
- A. The child may be born with diabetes.
- B. The child may be born with hypertension.
- C. The child may be born with an addiction to drugs.
- D. The child may be born with CNS defects.
Correct Answer: C
Rationale: The nurse informs the client that children born to mothers using addictive drugs are often born with an addiction to the drug. Children born to mothers who are addicted to cocaine are not known to be born with diabetes, CNS defects, or hypertension.
Kirk sprained his ankle and is asking for pain medication for his mild-to-moderate pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: A
Rationale: Ibuprofen is first-line for mild-to-moderate pain due to efficacy and safety.