Burns Pediatric Primary Care Test Bank Related

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the clinical manifestations of nephrosis include which of the following ?

  • A. hematuria, bacteriuria, weight gain.
  • B. gross hematuria, albuminuria, fever.
  • C. hypertension, weight loss, proteinuria.
  • D. massive proteinuria, hypoalbuminemia, edema.
Correct Answer: D

Rationale: Nephrosis, also known as nephrotic syndrome, is characterized by the presence of massive proteinuria (excretion of more than 3.5 grams of protein in the urine per day), hypoalbuminemia (low levels of albumin in the blood), and edema (swelling due to fluid retention). These are the hallmark clinical manifestations of nephrosis. Proteinuria results from damage to the glomerular filtration barrier, leading to the loss of proteins, particularly albumin, in the urine. Hypoalbuminemia occurs due to the excessive loss of albumin in the urine, leading to reduced oncotic pressure in the bloodstream. Edema develops as a result of decreased oncotic pressure, which causes fluid to leak from the blood vessels into the tissues, especially in the lower extremities and around the eyes. Other common manifestations of nephrosis may include hyperlipidemia, lipid