Nokea
The major factor in terminating the action of ethanol is
- A. Biotransformation
- B. Excretion through lungs
- C. Excretion unchanged in urine
- D. Excretion in feces
Correct Answer: A
Rationale: Ethanol is primarily metabolized by the liver (biotransformation) via alcohol dehydrogenase.
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The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurses most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.
What medication most likely caused patient's hypoglycaemia?
- A. Acarbose
- B. Exenatide
- C. Glyburide
- D. Metformin
Correct Answer: C
Rationale: Glyburide, a sulfonylurea, is most likely to cause hypoglycemia due to excessive insulin release.
Besides osteoporosis, IV bisphosphonates are also indicated for:
- A. Paget's Disease
- B. Early osteopenia
- C. Renal cancer
- D. Early closure of cranial sutures
Correct Answer: A
Rationale: IV bisphosphonates treat Paget's disease by reducing bone turnover; osteopenia uses oral forms typically.
Cost-effectiveness analysis compares two or more treatments or programs that are:
- A. Not necessarily therapeutically equivalent
- B. Considered equal in efficacy
- C. Compared with the dollar value of the benefit received
- D. Expressed in terms of patient preference or quality-adjusted life years
Correct Answer: A
Rationale: Cost-effectiveness analysis evaluates treatments that may differ in efficacy.
The Combination of amoxycillin + clavulanic acid is used because
- A. It broadens the spectrum of amoxycillin
- B. It decreases the side effect of amoxycillin
- C. It decreases the toxicity of clavulanic acid
- D. It increases the oral bio availability of amoxycillin
Correct Answer: A
Rationale: Clavulanic acid inhibits beta-lactamases, broadening amoxicillin's spectrum.