Nokea
The major part of the aqueous component (other than water) of pancreatic juice is
- A. mucus.
- B. trypsinogen, chymotrypsinogen, and procarboxypeptidase.
- C. bicarbonate ions.
- D. secretin.
Correct Answer: C
Rationale: The correct answer is C: bicarbonate ions. Pancreatic juice is alkaline to neutralize the acidic chyme entering the small intestine from the stomach. Bicarbonate ions are secreted by pancreatic duct cells and play a major role in maintaining the pH balance. Mucus (choice A) is produced by goblet cells and helps protect the lining of the digestive tract but is not a major component of pancreatic juice. Trypsinogen, chymotrypsinogen, and procarboxypeptidase (choice B) are pancreatic enzymes, not the major component of the aqueous component. Secretin (choice D) is a hormone that stimulates the pancreas to release bicarbonate ions but is not a component of pancreatic juice itself.
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Which of the following statements regarding caloric restriction (CR) is TRUE?
- A. CR stimulates the insulin signalling pathway, leading to activation of longevity genes
- B. resveratrol can mimic the effects of caloric restriction in worms, yeast and flies
- C. CR has been demonstrated to increase life span in humans
- D. all of the above are true
Correct Answer: B
Rationale: The correct answer is B: Resveratrol can mimic the effects of caloric restriction in worms, yeast, and flies. This is true because resveratrol, a compound found in red wine, has been shown to activate certain proteins and enzymes that are also activated during caloric restriction, leading to improved health and longevity in these organisms.
A is incorrect because caloric restriction typically leads to decreased insulin signaling, not stimulation. C is incorrect because while CR has been shown to increase lifespan in various animal models, there is limited evidence to support its effects on human lifespan. D is incorrect because not all statements are true - only B is supported by scientific evidence.
The colonic microflora can be considered as 'an organ within an organ'. Which of the following statements best describes the functions of the microbiota?
- A. Measurement of daily dietary fibre intake underestimates the amount of fermentable material entering the colon each day
- B. All of the options given are correct
- C. Acetate, propionate and butyrate are the chief organic acids produced by anaerobic colic fermentation
- D. The establishment of an 'acetate buffer' in the colonic lumen suppresses the growth of some pathogenic bacteria.
Correct Answer: B
Rationale: The correct answer is B because the colonic microbiota performs multiple essential functions such as aiding in digestion, producing vitamins, regulating immune function, and maintaining gut barrier integrity. Option A is incorrect as it focuses on dietary fiber intake rather than the microbiota's functions. Option C is incorrect because while acetate, propionate, and butyrate are important organic acids produced, they are not the only ones. Option D is incorrect as the microbiota's establishment of an 'acetate buffer' does not necessarily suppress the growth of all pathogenic bacteria.
The nurse needs to administer feedings to a client who has diarrhea due to gastroenteritis. Which of the following factors should the nurse consider?
- A. Administer feedings at room temperature
- B. Administer cold feedings
- C. Administer bolus feedings
- D. Administer intermittent feedings
Correct Answer: A
Rationale: Room temperature feedings reduce gastric irritation, which can help prevent worsening diarrhea.
Once absorbed into the epithelial cell of the small intestine, free fatty acids and glycerol are recombined and a protein coat is added to form a
- A. chylomicron.
- B. micelle.
- C. lipoprotein.
- D. fatty droplet.
Correct Answer: A
Rationale: The correct answer is A: chylomicron. After absorption, free fatty acids and glycerol are recombined in the epithelial cell to form triglycerides. These triglycerides are then packaged with proteins to form chylomicrons, which are lipoprotein particles that transport dietary fats through the lymphatic system and bloodstream. Chylomicrons are essential for the absorption of dietary fats and fat-soluble vitamins.
Summary:
- B: Micelle is incorrect because micelles are formed in the lumen of the small intestine to aid in the absorption of lipids but do not involve recombination of fatty acids and glycerol.
- C: Lipoprotein is incorrect because while chylomicrons are a type of lipoprotein, the specific process described in the question is not about general lipoprotein formation.
- D: Fatty droplet is incorrect as it does not involve the recombination and protein coating process described in the question.
What is the patient with chronic pancreatitis more likely to have than the patient with acute pancreatitis?
- A. The need to abstain from alcohol
- B. Experience acute abdominal pain
- C. Malabsorption and diabetes mellitus
- D. Require a high-carbohydrate, high-protein, low-fat diet
Correct Answer: C
Rationale: Chronic pancreatitis often leads to malabsorption and diabetes mellitus due to long-term pancreatic dysfunction.