Nokea
What is the normal range for the hematocrit value in a healthy adult?
- A. 20-40%
- B. 40-60%
- C. 60-80%
- D. 80-100%
Correct Answer: B
Rationale: The correct answer is B: 40-60%. Hematocrit represents the percentage of red blood cells in the blood. The normal range for hematocrit in a healthy adult is typically around 40-60%. Values below 40% may indicate anemia, while values above 60% may suggest conditions like dehydration or polycythemia. Choices A, C, and D are incorrect because they fall outside the normal range for hematocrit levels in a healthy adult.
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Ferrets have recently been objects of an intense debate within the scientific community in the field of Flu research because
- A. Of a recent outbreak caused by a novel Influenza strain
- B. Of a recent outbreak caused by a highly virulent H1N1 strain
- C. Mutations have been introduced in H5N1 creating a strain transmissible among these mammals
- D. Two publications on this animal model for Flu were put on hold due to biosecurity reasons
Correct Answer: C
Rationale: The correct answer is C because it indicates a specific reason for the intense debate within the scientific community regarding ferrets in Flu research. Mutations in H5N1 creating a strain transmissible among ferrets is significant as it highlights a potential threat of cross-species transmission and the need for further study.
A is incorrect as it does not provide a specific reason related to ferrets and their role in Flu research. B is incorrect because it focuses on a specific strain (H1N1) rather than mutations in H5N1. D is incorrect as it mentions publications being put on hold but does not address the core issue of mutations and transmissibility among ferrets.
The vascular instability observed in severe sepsis is caused by
- A. Systemic release of cytokines such as TNF-α and IL-1β
- B. Complement activation
- C. Release of high levels of lipid mediators
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D because all the choices contribute to the vascular instability observed in severe sepsis. A: Systemic release of cytokines like TNF-α and IL-1β leads to vasodilation and increased capillary permeability. B: Complement activation causes inflammation and vasodilation. C: Release of high levels of lipid mediators like prostaglandins and leukotrienes further exacerbates vasodilation and vascular permeability. Therefore, all these mechanisms combined lead to the vascular instability seen in severe sepsis.
What is the consequence of granzyme entering a target cell?
- A. Neutralization of toxins
- B. Activation of apoptosis pathways
- C. Inhibition of cytokine secretion
- D. Promotion of antigen presentation
Correct Answer: B
Rationale: Granzyme entering a target cell activates apoptosis pathways by inducing cell death. Firstly, granzyme activates caspases leading to cell death. Secondly, it triggers DNA fragmentation and cell shrinkage. Lastly, it enhances membrane blebbing and apoptotic body formation. The other choices are incorrect because granzyme does not neutralize toxins, inhibit cytokine secretion, or promote antigen presentation within a target cell.
What factor differentiates a malignant tumor from a benign tumor?
- A. It causes death
- B. It grows at a faster rate
- C. It is often encapsulated
- D. It invades and metastasizes
Correct Answer: D
Rationale: Malignant tumors invade surrounding tissues and can metastasize to distant sites, whereas benign tumors do not exhibit these characteristics.
An 82-year-old male patient with pneumonia who is in the intensive care unit (ICU) is beginning to have decreased cognitive function. What should the nurse first suspect as a potential cause of this change?
- A. Fatigue
- B. Infection
- C. ICU psychosis
- D. Medication allergy
Correct Answer: C
Rationale: ICU psychosis is common in elderly patients due to sensory overload, sleep deprivation, and unfamiliar environments. While infection could also cause confusion, ICU psychosis is more likely given the context.