Nokea
When caring for a patient with primary hyperaldosteronism, the nurse would question a health care provider's prescription for which drug?
- A. Furosemide (Lasix)
- B. Spironolactone (Aldactone)
- C. Amiloride (Midamor)
- D. Aminoglutethimide (Cytadren)
Correct Answer: A
Rationale: Furosemide (Lasix) is a diuretic that can exacerbate hypokalemia, which is already a concern in primary hyperaldosteronism. Spironolactone, Amiloride, and Aminoglutethimide can be more appropriate for managing the condition.
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Your patient is diagnosed with myasthenia gravis, and she is given a prescription for pyridostigmine. Which of the following best summarizes the drug’s mechanism of action?
- A. Blocks muscarinic receptors, so that acetylcholine preferentially stimulates skeletal muscle
- B. Inhibits reuptake of acetylcholine by motor nerves
- C. Inhibits skeletal muscle activation at rest so that the muscles are less susceptible to fatigue during exercise
- D. Inhibits breakdown of acetylcholine, thereby improving activation of skeletal muscle by acetylcholine
Correct Answer: D
Rationale: The correct answer is D: "Inhibits breakdown of acetylcholine, thereby improving activation of skeletal muscle by acetylcholine."
Rationale:
1. Pyridostigmine is an acetylcholinesterase inhibitor, which means it blocks the breakdown of acetylcholine.
2. In myasthenia gravis, there is a decrease in acetylcholine receptor sites, leading to muscle weakness.
3. By inhibiting the breakdown of acetylcholine, pyridostigmine increases the availability of acetylcholine at the neuromuscular junction, improving muscle activation.
4. This mechanism helps alleviate muscle weakness in myasthenia gravis patients.
Summary:
A: Incorrect. Pyridostigmine does not block muscarinic receptors or change the preference of acetylcholine stimulation.
B: Incorrect. Pyridostigmine does not inhibit reuptake of acetylcholine; it acts by inhibiting its breakdown
What is the distance travelled by the car in the 20 s shown?
- A. 80 m
- B. 100 m
- C. 160 m
- D. 200 m
Correct Answer: C
Rationale: The correct answer is C: 160 m. To calculate distance traveled, we use the formula: distance = speed x time. In this case, the speed of the car is 8 m/s (given in the graph) and the time is 20 s. Therefore, distance = 8 m/s x 20 s = 160 m. Choice A is incorrect as it is too low. Choice B is incorrect as it does not account for the full 20 s. Choice D is incorrect as it is too high based on the given speed and time.
The endocrine system works together with the ________ system to maintain the body’s equilibrium?
- A. digestive system
- B. nervous system
- C. respiratory system
- D. reproductive system
Correct Answer: B
Rationale: The correct answer is B: nervous system. The endocrine system and nervous system work together in maintaining the body's equilibrium through communication and regulation of bodily functions. The nervous system controls rapid responses, while the endocrine system regulates slower, long-term responses through hormones. The digestive system (A) primarily focuses on breaking down food and absorbing nutrients. The respiratory system (C) is responsible for gas exchange. The reproductive system (D) is involved in reproduction and hormone production, but not in maintaining the body's equilibrium.
Thyroid hormone (a small iodinated amine) enters target cells in a manner similar to ________.
- A. insulin, because insulin is a small peptide
- B. steroid hormones, because both diffuse easily into target cells
- C. growth hormone, because the thyroid works synergistically with thyroid hormone
- D. glucagon, because the structure of glucagon is similar to that of thyroid hormone
Correct Answer: B
Rationale: The correct answer is B: steroid hormones, because both diffuse easily into target cells. Thyroid hormone, being a small iodinated amine, can easily pass through the cell membrane and bind to intracellular receptors, similar to steroid hormones. Unlike insulin (choice A), which binds to cell surface receptors, thyroid hormone and steroid hormones enter the cell to exert their effects. Growth hormone (choice C) and glucagon (choice D) do not share the same mechanism of entry into target cells as thyroid hormone, making them incorrect choices.
Which endocrine gland is known as the master gland?
- A. Adrenal
- B. Liver
- C. Pancreas
- D. Pituitary
Correct Answer: D
Rationale: The correct answer is D: Pituitary gland. The pituitary gland is known as the master gland because it controls the functions of other endocrine glands in the body by secreting various hormones that regulate growth, reproduction, metabolism, and other essential bodily functions. It is located at the base of the brain and plays a crucial role in maintaining hormonal balance.
Explanation for other choices:
A: Adrenal gland primarily regulates stress response and metabolism.
B: Liver is not an endocrine gland; it is involved in metabolism and detoxification.
C: Pancreas is responsible for regulating blood sugar levels through insulin and glucagon secretion but is not known as the master gland.