When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to take effect (onset of action) after administration?
- A. 15 to 30 minutes
- B. 60 to 90 minutes
- C. 3 to 4 hours
- D. 6 to 8 hours
Correct Answer: B
Rationale: NPH insulin has an onset of 60-90 minutes; shorter is rapid-acting, longer is basal.
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Which of the following is not a dose related reaction:
- A. Myocardial Irritation of Quinidine
- B. Hypoglycemia of tolbutamide
- C. Digitalis induced arrythmia
- D. Drug fever of sulpha
Correct Answer: D
Rationale: Drug fever from sulfa is an idiosyncratic/hypersensitivity reaction, not dose-related.
The client has begun medication therapy with pancrelipase (Pancrease MT). The nurse evaluates that the medication is having the optimal intended benefit if which effect is observed?
- A. Weight loss
- B. Relief of heartburn
- C. Reduction of steatorrhea
- D. Absence of abdominal pain
Correct Answer: C
Rationale: Pancrelipase (Pancrease MT) is a pancreatic enzyme used in clients with pancreatitis as a digestive aid. The medication should reduce the amount of fatty stools (steatorrhea). Another intended effect could be improved nutritional status. It is not used to treat abdominal pain or heartburn. Its use could result in weight gain but should not result in weight loss if it is aiding in digestion.
A nurse is preparing to administer Propranolol to a client who has a dysrhythmia. Which of the following actions should the nurse plan to take?
- A. Hold propranolol for an apical pulse greater than 100/min.
- B. Administer propranolol to increase the client's blood pressure.
- C. Assist the client when she sits up or stands after taking this medication.
- D. Check for hypokalemia frequently due to the risk for propranolol toxicity.
Correct Answer: C
Rationale: Propranolol can cause orthostatic hypotension; assisting with position changes prevents falls.
Please select a correct statement:
- A. Steroids excreted in maximal amount in evening and night time - between 20-24 h
- B. Steroids maximal excretion is in morning time - between -4-8 h
- C. Steroids maximal secretion is in daytime- between -12-16 h
- D. Steroids decrease sensitivity of vessels and bronchus towards catecholamines
Correct Answer: B
Rationale: Steroids peak in the morning (4-8 AM) due to circadian rhythm of cortisol secretion.
The following can be used for diabetes mellitus:
- A. Desmoporesine
- B. Insuline preparations
- C. Chlorpropamide
- D. Metformin
Correct Answer: A
Rationale: Insulin, chlorpropamide, metformin, and acarbose (B, C, D, E) are all used for diabetes management.