Nokea
Which medication route provides the most rapid onset of a medication, but also poses the greatest risk of adverse effects?
- A. Intradermal
- B. Subcutaneous (subcut)
- C. Intramuscular (IM)
- D. Intravenous (IV)
Correct Answer: D
Rationale: IV medications are delivered directly into the bloodstream and avoid the first pass effect of the liver. Intradermal, subcut, and IM administration have a slower absorption rate.
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The routine monitoring recommended for low molecular weight heparin is:
- A. INR every 2 days until stable, then weekly
- B. aPTT every week while on therapy
- C. Factor Xa levels if the patient is pregnant
- D. White blood cell count every 2 weeks
Correct Answer: C
Rationale: Factor Xa levels may be monitored in pregnancy with LMWH; routine INR or aPTT isn't needed due to predictable pharmacokinetics.
Not a prodrug
- A. Lisinopril
- B. Enalapril
- C. Ramipril
- D. Famotidine
Correct Answer: A
Rationale: Lisinopril is active; others are prodrugs.
A 15 year old girl experiences epileptic fits during her menstrual periods. Which ONE of the following drugs is best suited for the management of her condition?
- A. Ethosuximide
- B. Valproic acid
- C. Phenytoin
- D. Corticosteroids
Correct Answer: B
Rationale: Valproic acid is effective for catamenial epilepsy and tonic-clonic seizures.
This graph illustrates the dose-response relationship for the effect of the beta agonist isoproterenol on an isolated perfused heart, both alone and in the presence of different fixed concentrations of Drug X. Based upon the data shown, Drug X is most likely a(n):
- A. beta agonist
- B. competitive antagonist
- C. irreversible antagonist
- D. noncompetitive antagonist
Correct Answer: A
Rationale: Without the graph, the answer key indicates Drug X is a beta agonist, suggesting it enhances or mimics isoproterenol's effect, likely shifting the curve upward or leftward.
A nurse is caring for a client who has a new prescription for Phenelzine for the treatment of depression. Which of the following indicates that the client has developed an adverse effect of this medication?
- A. Orthostatic hypotension
- B. Hearing loss
- C. Gastrointestinal bleeding
- D. Weight loss
Correct Answer: A
Rationale: Phenelzine, an MAOI, commonly causes orthostatic hypotension due to its effect on blood pressure regulation.