Nokea
Which of the following anti-HIV regimen that is generally reserved for * advanced cases of AIDS or for repeated treatment failures?:
- A. Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI)
- B. Three NRTIs
- C. Two NRTIs + one non-NRTI
- D. One NRTI + one non-NRTI + one PI
Correct Answer: A
Rationale: The correct answer is A: Two nucleoside reverse transcriptase inhibitors (NRTIs) + one protease inhibitor (PI). This regimen is typically reserved for advanced cases of AIDS or repeated treatment failures due to its potent antiviral effects. NRTIs inhibit viral replication by interfering with the HIV enzyme reverse transcriptase, while PIs inhibit the enzyme protease, essential for viral maturation. Combining these two classes of drugs provides a strong barrier against HIV resistance. Other choices (B, C, D) are less effective in advanced cases as they do not provide the same level of dual inhibition necessary to combat resistant strains and advanced disease progression.
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The process of voiding urine from the enhanced by: bladder is known as:
- A. large surface area of the capillaries
- B. menstruation
- C. large numbers of glomeruli
- D. implantation
Correct Answer:
Rationale: Correct Answer: C: large numbers of glomeruli
Rationale:
1. The process of voiding urine involves the filtration of blood in the kidneys.
2. Glomeruli are the kidney structures responsible for filtering blood and forming urine.
3. Having a large number of glomeruli increases the efficiency of urine production and filtration.
4. Therefore, the presence of large numbers of glomeruli enhances the process of voiding urine.
Summary:
A: Large surface area of capillaries - This does not directly relate to the process of voiding urine but rather to blood circulation.
B: Menstruation - Menstruation is a reproductive process and not related to voiding urine.
D: Implantation - Implantation refers to the attachment of a fertilized egg in the uterus and is not related to voiding urine.
Which of the following drug is a radical curative in plasmodium vivax malaria * and is used as prophylaxis for malaria at Chloroquine sensitive regions
- A. Quinine
- B. Primaquine
- C. Meoquine
- D. Chloroquine
Correct Answer: B
Rationale: The correct answer is B: Primaquine. Primaquine is a radical curative drug for Plasmodium vivax malaria, as it targets the hypnozoite stage in the liver, preventing relapses. It is also used as prophylaxis in Chloroquine-sensitive regions due to its efficacy against P. vivax and P. ovale.
Rationale:
1. Quinine (A) is not a radical curative drug for P. vivax malaria. It is mainly used for treatment of acute malaria.
2. Meoquine (C) is not a radical curative drug for P. vivax malaria and is used more for prophylaxis in certain regions.
3. Chloroquine (D) is not a radical curative drug for P. vivax malaria and is primarily used for treatment and prevention of malaria caused by susceptible strains of Plasmodium species.
During an examination, the nurse observes a female patient's vestibule and expects to see the:
- A. Urethral meatus and vaginal orifice.
- B. Vaginal orifice and vestibular (Bartholin) glands.
- C. Urethral meatus and paraurethral (Skene) glands.
- D. Paraurethral (Skene) and vestibular (Bartholin) glands.
Correct Answer: A
Rationale: The correct answer is A: Urethral meatus and vaginal orifice. The vestibule is the area between the labia minora where the urethral meatus and vaginal orifice are located. This is important for the nurse to observe during an examination to assess the patient's genital health.
Choice B is incorrect because the vestibular (Bartholin) glands are not typically visible in the vestibule during an examination. Choice C is incorrect because the paraurethral (Skene) glands are not typically visible in the vestibule either. Choice D is incorrect because it combines the paraurethral (Skene) and vestibular (Bartholin) glands, which are not typically visible in the vestibule during examination.
Patients with bladder cancer typically exhibit symptoms of:
- A. Weight loss and low back pain.
- B. Fatigue and anemia.
- C. Hematuria and change in urinary pattern.
- D. Difficulty initiating urinary stream and nocturia.
Correct Answer: C
Rationale: The correct answer is C because hematuria (blood in urine) and change in urinary pattern are classic symptoms of bladder cancer. Hematuria is the most common presenting symptom. Weight loss and low back pain (choice A) are more indicative of advanced stages of cancer. Fatigue and anemia (choice B) are nonspecific symptoms. Difficulty initiating urinary stream and nocturia (choice D) may be seen in other conditions but are not specific to bladder cancer.
Which of the following antiviral drug most commonly used drug for prevention and treatment of CMV infections in the immunocompromised patients?
- A. Ganciclovir
- B. Indinavir
- C. Amantadine
- D. Foscarnet
Correct Answer: A
Rationale: Rationale:
1. Ganciclovir is the preferred antiviral for CMV infections due to its effectiveness against CMV.
2. It works by inhibiting viral DNA polymerase, stopping viral replication.
3. Indinavir is a protease inhibitor used for HIV, not CMV.
4. Amantadine is used for influenza A virus, not CMV.
5. Foscarnet is an alternative for CMV if ganciclovir is not tolerated.