Nokea
A nurse is teaching the parents of a school-age child about transdermal Methylphenidate. Which of the following instructions should the nurse include?
- A. Apply one patch twice per day.
- B. Leave the patch on for 9 hr.
- C. Apply the patch to the child's waist.
- D. Use opened tray within 6 months.
Correct Answer: B
Rationale: Methylphenidate patches are worn for 9 hours to control ADHD symptoms during the day.
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Which cytochrome is responsible for drug metabolism?
- A. P-450
- B. C-3b
- C. C-3a
- D. C-2a
Correct Answer: A
Rationale: Cytochrome P-450 enzymes in the liver are primary for drug metabolism.
Which of the following statements about aminoglycosides is false?
- A. They have short half-lives
- B. They are bactericidal
- C. They exacerbate weakness in myasthenia gravis patients
- D. None of the Above
Correct Answer: D
Rationale: All statements are true: aminoglycosides have short half-lives (2-3 hours), are bactericidal, and can worsen myasthenia gravis by neuromuscular blockade.
A nurse is assessing the patient's home medication use. After listening to the patient list current medications, the nurse asks what priority question?
- A. Do you take any generic medications?
- B. Are any of these medications orphan drugs?
- C. Are these medications safe to take during pregnancy?
- D. Do you take any over-the-counter medications?
Correct Answer: D
Rationale: It is important for the nurse to specifically question use of over-the-counter medications because patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs unless they too are health care providers. Safety during pregnancy, use of a generic medication, or classification of orphan drugs are things the patient would be unable to answer but could be found in reference books if the nurse wishes to research them.
The trial period to determine effective anti-inflammatory activity when starting a patient on aspirin for rheumatoid arthritis is:
- A. 48 hours
- B. 4 to 6 days
- C. 4 weeks
- D. 2 months
Correct Answer: B
Rationale: Aspirin's anti-inflammatory effect for RA takes 4-6 days; 48 hours is too short.
In choosing a benzodiazepam to treat anxiety the prescriber needs to be aware of the possibility of dependence. The benzodiazepam with the greatest likelihood of rapidly developing dependence is:
- A. Chlordiazepoxide (Librium)
- B. Clonazepam (Klonopin)
- C. Alprazolam (Xanax)
- D. Oxazepam (Serax)
Correct Answer: C
Rationale: Alprazolam's short half-life increases dependence risk.