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A 10-year-old boy is diagnosed with Attention Deficit/Attention Deficit-Hyperactivity disorder (ADD/ADHD). Which of the following drugs is most likely to prove effective for relieving the boy’s main symptoms?
- A. Dobutamine
- B. Amphetamine
- C. Pancuronium
- D. Prazosin
Correct Answer: B
Rationale: The correct answer is B: Amphetamine. Amphetamine is a stimulant commonly used to treat symptoms of ADHD as it helps improve focus, impulse control, and hyperactivity. It works by increasing the levels of certain neurotransmitters in the brain. Dobutamine (A) is a different type of stimulant used for heart conditions. Pancuronium (C) is a muscle relaxant used during surgery, and Prazosin (D) is an alpha-blocker used for high blood pressure and PTSD nightmares. Therefore, Amphetamine is the most likely drug to be effective for relieving the boy's main symptoms of ADHD.
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The following statements concerning prazosin and phentolamine are correct EXCEPT:
- A. Both antagonize alpha1-receptors
- B. Both cause the same degree of tachycardia
- C. Both decrease blood pressure
- D. Both are competitive antagonists
Correct Answer: B
Rationale: Correct Answer: B
Rationale:
1. Prazosin and phentolamine both antagonize alpha1-receptors, leading to vasodilation and decreased blood pressure.
2. Both drugs are competitive antagonists, competing with norepinephrine at alpha1-receptors.
3. However, phentolamine causes reflex tachycardia due to its non-selective alpha-adrenergic blockade, unlike prazosin.
4. Therefore, the statement that both cause the same degree of tachycardia is incorrect based on their pharmacological differences.
Which is a nutritionally essential amino acid?
- A. taunine
- B. leucine
- C. glutamate
- D. alanine
Correct Answer: B
Rationale: Rationale for correct answer (B - leucine): Leucine is an essential amino acid, meaning it cannot be synthesized by the body and must be obtained through diet. It plays a crucial role in protein synthesis, muscle repair, and growth. It is essential for overall health and well-being.
Summary of why other choices are incorrect:
A - taurine: Taurine is a conditionally essential amino acid, not nutritionally essential.
C - glutamate: Glutamate is a non-essential amino acid, as the body can synthesize it.
D - alanine: Alanine is a non-essential amino acid, as the body can also produce it.
Isoprenaline produces the following actions EXCEPT:
- A. Direct stimulation of beta adrenoceptors
- B. Relaxation of bronchial smooth muscles
- C. Decreased blood pressure
- D. Increased intestinal motility
Correct Answer: D
Rationale: Step-by-step rationale:
1. Isoprenaline is a beta-adrenergic agonist.
2. It directly stimulates beta adrenoceptors, leading to effects like increased heart rate.
3. Isoprenaline causes bronchodilation by relaxing bronchial smooth muscles.
4. It also causes vasodilation, leading to decreased blood pressure.
5. Isoprenaline does not have a direct effect on intestinal motility, making option D incorrect.
Summary:
Option D is incorrect as isoprenaline does not increase intestinal motility. Options A, B, and C are correct as isoprenaline directly stimulates beta adrenoceptors, relaxes bronchial smooth muscles, and decreases blood pressure, respectively.
What manifestations of endocrine problems in the older adult are commonly attributed to the aging process?
- A. Tremors and paresthesias
- B. Fatigue and mental impairment
- C. Hyperpigmentation and oily skin
- D. Fluid retention and hypertension
Correct Answer: B
Rationale: Fatigue and mental impairment are often attributed to normal aging but may indicate an underlying endocrine disorder such as hypothyroidism or adrenal insufficiency.
You are preparing to review a teaching plan for a patient with type 2 diabetes. What will you check to determine the patient's level of compliance with his diabetic regimen?
- A. Patient's fasting glucose level
- B. Patient's oral glucose tolerance test results
- C. Patient's glycosylated hemoglobin assay
- D. Patient's fingerstick glucose check for 24 hours
Correct Answer: C
Rationale: The glycosylated hemoglobin assay (HbA1c) provides an average blood glucose level over the past 2-3 months and is the best indicator of long-term compliance with the diabetic regimen.