Endocrine System Test Questions Related

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A patient presents with weight loss, sweating, palpitations, tachycardia, tremors, lid lag, exopthalmosis, and a goiter. Upon taking a thyroid scan, there appears to be an increased amount of iodine. What is the pathogenesis of his disease?

  • A. Autoimmune Mediated
  • B. Immune Complex Mediated
  • C. Unknown
  • D. Infection
Correct Answer: A

Rationale: The correct answer is A: Autoimmune Mediated. In this case, the patient is presenting with symptoms of hyperthyroidism along with a goiter, which is indicative of Graves' disease, an autoimmune disorder where antibodies stimulate the thyroid gland to produce excess thyroid hormones. The presence of increased iodine uptake in the thyroid scan supports this diagnosis. On the other hand, immune complex mediated diseases typically involve tissue damage caused by immune complexes, not thyroid hormone excess. The cause being unknown or infection-related are not consistent with the symptoms and thyroid scan findings in this case.