Which hormone is produced by the pancreas and acts on the liver to increase blood glucose levels?
- A. glucagon; liver
- B. melatonin; liver
- C. glucagon; kidney
- D. calcitonin; thyroid
Correct Answer: A
Rationale: The correct answer is A: glucagon is produced by the pancreas and acts on the liver to increase blood glucose levels. Glucagon triggers the liver to break down glycogen into glucose, releasing it into the bloodstream. Melatonin is a hormone produced by the pineal gland and is not involved in glucose regulation. Glucagon does not act on the kidney but specifically targets the liver. Calcitonin is produced by the thyroid gland and plays a role in calcium regulation, not glucose metabolism.
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Which of the following best describes the function of insulin?
- A. Lowers blood glucose levels.
- B. Stimulates cells to make glucose (gluconeogenesis).
- C. Deficiency causes diabetes insipidus.
- D. Decreases blood volume.
Correct Answer: A
Rationale: The correct answer is A: Lowers blood glucose levels. Insulin is a hormone produced by the pancreas that helps regulate blood glucose levels by promoting the uptake of glucose into cells for energy storage. This process reduces the concentration of glucose in the bloodstream. Choices B, C, and D are incorrect because insulin does not stimulate cells to make glucose (B), deficiency does not cause diabetes insipidus (C), and it does not directly affect blood volume (D).
A patient with mild iatrogenic Cushing syndrome is on an alternate-day regimen of corticosteroid therapy. What does the nurse explain to the patient about this regimen?
- A. It maintains normal adrenal hormone balance.
- B. It prevents ACTH release from the pituitary gland.
- C. It minimizes hypothalamic-pituitary-adrenal suppression.
- D. It provides a more effective therapeutic effect of the drug.
Correct Answer: C
Rationale: Alternate-day corticosteroid therapy minimizes hypothalamic-pituitary-adrenal axis suppression, which helps prevent long-term adrenal insufficiency.
Hyoscine produces all of the following actions EXCEPT:
- A. Sedation
- B. Antiemetic action
- C. Stimulation of the respiratory center
- D. Increase of salivary secretion
Correct Answer: D
Rationale: Hyoscine, also known as scopolamine, is an anticholinergic drug that acts by blocking muscarinic receptors. It produces sedation by crossing the blood-brain barrier and affecting the central nervous system. Its antiemetic action is due to its ability to inhibit the vomiting center in the brain. Stimulation of the respiratory center is not a typical action of hyoscine. Lastly, hyoscine decreases salivary secretion due to its anticholinergic effects. Therefore, the correct answer is D (Increase of salivary secretion) as it is inconsistent with the pharmacological actions of hyoscine.
The posterior pituitary stores and releases:
- A. Growth hormone & Prolactin
- B. Prolactin & Oxytocin
- C. Oxytocin & ADH
- D. ADH & GH
Correct Answer: C
Rationale: The correct answer is C: Oxytocin & ADH. The posterior pituitary stores and releases hormones produced by the hypothalamus. Oxytocin is responsible for uterine contractions during childbirth and milk ejection during breastfeeding. ADH (anti-diuretic hormone) regulates water balance by influencing the reabsorption of water by the kidneys. Growth hormone (GH) and Prolactin are released by the anterior pituitary, not the posterior pituitary. Therefore, choices A, B, and D are incorrect as they do not represent the hormones stored and released by the posterior pituitary.
A child visiting his grandfather at his farm returns home having fever, skin flush, dry mouth, constipation, dilated pupils, and increased heart rate. Which of the following could be the offending agent:
- A. Eating seeds containing atropine
- B. Exposure to malathion insecticide
- C. Wrong intake of echothiophate drops
- D. Ingestion of physostigmine
Correct Answer: A
Rationale: The correct answer is A: Eating seeds containing atropine. Atropine is a plant alkaloid commonly found in certain seeds that can cause symptoms such as fever, skin flush, dry mouth, constipation, dilated pupils, and increased heart rate when ingested. Atropine is known to have anticholinergic effects, which align with the symptoms presented by the child. Malathion (B) is an insecticide that typically causes different symptoms like nausea, vomiting, and diarrhea. Echothiophate drops (C) are cholinesterase inhibitors used in the treatment of glaucoma, which would not produce the described symptoms. Physostigmine (D) is a cholinesterase inhibitor that would not cause symptoms of anticholinergic toxicity seen in the child.