In which type of cell are ligand-gated ion channels most commonly found?
- A. Cells that are terminally differentiated
- B. Cells that produce large proteins
- C. Cells that need to respond quickly to external stimuli
- D. Cells that respond to mechanic forces
Correct Answer: C
Rationale: Ligand-gated ion channels enable rapid responses to stimuli, common in excitable cells like neurons and muscle cells.
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What dermatological issue is linked to Amiodarone use?
- A. Increased risk of basal cell carcinoma
- B. Flare up of any prior psoriasis problems
- C. Development of plantarwarts
- D. Progressive change of skin tone toward a blue spectrum
Correct Answer: D
Rationale: Amiodarone causes blue-gray skin discoloration due to drug deposition.
The following drugs are correctly paired with a clinical use EXCEPT:
- A. Danazol to treat endometriosis
- B. Flutamide to treat benign prostatic hyperplasia
- C. Finasteride to treat male pattern baldness
- D. Clomiphene to treat anovulatory infertility
Correct Answer: B
Rationale: Flutamide treats prostate cancer, not BPH; finasteride is used for BPH.
A nurse is providing teaching to a client who has a new prescription for Digoxin. The nurse should instruct the client to monitor and report which of the following adverse effects that is a manifestation Digoxin toxicity? (Select one that does not apply.)
- A. Fatigue
- B. Constipation
- C. Anorexia
- D. Diplopia
Correct Answer: B
Rationale: Fatigue , anorexia , and diplopia are signs of digoxin toxicity.
Beta blocker which has less first pass metabolism and more excretion through kidney is
- A. Propranolol
- B. Sotalol
- C. Bisprolol
- D. Nadolol
Correct Answer: B
Rationale: Sotalol has minimal first-pass metabolism and is excreted renally.
Which of the following drug increase the sensitivity of fatty tissue and muscles towards insulin:
- A. Dapagliphlozin
- B. Miglitol
- C. Nateglinide
- D. Rosiglitasone
Correct Answer: D
Rationale: Rosiglitazone, a thiazolidinedione, enhances insulin sensitivity in fat and muscle via PPAR-gamma activation.
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