Nokea
Phil is starting treatment with febuxostat (Uloric). Education of patients starting febuxostat includes:
- A. Gout may worsen with therapy
- B. Febuxostat may cause severe diarrhea
- C. He should consume a high-calcium diet
- D. He will need frequent CBC monitoring
Correct Answer: A
Rationale: Febuxostat can initially worsen gout as uric acid mobilizes; diarrhea or calcium aren't emphasized.
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Tick the second messenger of G-protein-coupled (metabotropic) receptor:
- A. Adenylyl cyclase
- B. Sodium ions
- C. Phospholipase C
- D. cAMP
Correct Answer: D
Rationale: cAMP is a classic second messenger generated by G-protein-coupled receptors via adenylyl cyclase.
Which example best demonstrates safe drug administration by the nurse?
- A. Administering an oral medication with the patient sitting upright
- B. Asking children to say their name before administering the medication
- C. Leaving the medications on the bedside stand after verifying patient identification
- D. Returning the unused portion of a medication to a stock supply bottle
Correct Answer: A
Rationale: Sitting the patient upright for oral medications is safe medication practice. Children should never be asked their names as a means of positive identification. Remaining with a patient until the drug is swallowed is safe practice. Returning an unused portion of medication to the stock supply bottle is not safe medication practice.
Taking which drug with food maximizes it bioavailability?
- A. Donepezil
- B. Galantamine
- C. Rivastigmine
- D. Memantine
Correct Answer: C
Rationale: Rivastigmine's bioavailability is maximized with food, reducing GI side effects.
While providing medications to clients on the cardiac unit, the nurse anticipates that hydralazine hydrochloride and isosorbide dinitrate (BiDil) would most likely be prescribed for which of the following clients?
- A. A 48-year-old Caucasian male diagnosed with atrial fibrillation
- B. A 55-year-old African American female diagnosed with hypertension
- C. A 63-year-old Caucasian female diagnosed with sick sinus syndrome
- D. A 64-year-old African American male diagnosed with heart failure
Correct Answer: D
Rationale: BiDil (hydralazine/isosorbide) is FDA-approved specifically for heart failure in African Americans , showing improved outcomes in this population.
Midazolam as compared to diazepam is:
- A. Less cerebroprotective
- B. More cerebroprotective
- C. Same as diazepam
- D. No cerebroprotective effect
Correct Answer: A
Rationale: Midazolam is less cerebroprotective than diazepam.