Nokea
Which of the following is a primary lymphoid organ?
- A. Spleen
- B. Thymus
- C. Lymph node
- D. Mucosal immune system
Correct Answer: B
Rationale: The correct answer is B: Thymus. The thymus is considered a primary lymphoid organ because it is where T lymphocytes (T cells) mature and differentiate. T cells play a crucial role in the adaptive immune response. The thymus is responsible for educating T cells to recognize self versus non-self antigens.
Summary:
A: Spleen is a secondary lymphoid organ involved in filtering blood and producing antibodies, not where T cells mature.
C: Lymph node is also a secondary lymphoid organ where immune cells interact but not where T cells mature.
D: Mucosal immune system refers to the immune system in mucosal tissues, not a specific primary lymphoid organ.
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Which characteristic corresponds with the acute stage of HIV infection?
- A. Burkitt’s lymphoma
- B. Temporary fall of CD4+ T cells
- C. Persistent fevers and night sweats
- D. Pneumocystis jiroveci pneumonia
Correct Answer: B
Rationale: During the acute stage of HIV infection, there is a temporary decline in CD4+ T cell counts followed by rebounding levels. Symptoms such as fever and night sweats may occur but are not definitive characteristics of this stage.
A nurse has presented an educational program to a community group on Lyme disease. What statement by a participant indicates the need to review the material?
- A. I should take precautions against ticks, especially in the summer.
- B. A red rash that looks like a bull's-eye may be one of the symptoms.
- C. If Lyme disease is not treated successfully, it is usually fatal.
- D. For Stage I disease, antibiotics are usually needed for 14 to 21 days.
Correct Answer: C
Rationale: Step 1: Lyme disease is rarely fatal if treated promptly.
Step 2: Choice C states that Lyme disease is usually fatal if not treated successfully, which is incorrect.
Step 3: Therefore, this statement indicates a need for review as it spreads misinformation.
Step 4: Choices A, B, and D are accurate and align with the information provided in the educational program.
Step 5: In summary, the need to review the material is highlighted by the inaccurate statement in choice C, as the other choices provide correct information on Lyme disease.
A patient with chronic hepatitis C has been receiving interferon alfa-2a (Roferon-A) injections for the last month. Which information gathered during a visit in the home to conduct an interview and physical assessment is most important to communicate to the physician?
- A. The patient has chronic nausea and vomiting.
- B. The patient is giving the medication by the IM route to her lateral thigh.
- C. The patient has a temperature of 99.7°F orally.
- D. The patient complains of chronic fatigue,muscle aches and anorexia.
Correct Answer: A
Rationale: Chronic nausea and vomiting can lead to dehydration and malnutrition which are serious complications that need to be addressed. While the other symptoms are common side effects of interferon therapy they are less urgent than persistent nausea and vomiting.
A patient prescribed corticosteroids for arthritis is surprised to learn of an immune disorder. What should the nurse explain as the reason for the patient not demonstrating typical signs of immune dysfunction?
- A. The arthritis is masking the normal immune response.
- B. The corticosteroids are causing the thymus gland to malfunction.
- C. The arthritis is interfering with the function of immunoglobulins.
- D. Corticosteroids are impacting normal immune response functioning.
Correct Answer: D
Rationale: The correct answer is D because corticosteroids are known to suppress the immune system by inhibiting the production of pro-inflammatory cytokines and preventing the activation of immune cells. This suppression can lead to a decreased immune response, making it less likely for the patient to exhibit typical signs of immune dysfunction.
A: The arthritis masking the immune response is not a plausible explanation as arthritis does not directly affect immune function.
B: Corticosteroids do not cause the thymus gland to malfunction; they mainly impact immune response at the cellular level.
C: Arthritis affecting immunoglobulin function is not a common mechanism of immune dysfunction in this context.
Prophylactic measures that are routinely used as early as possible in HIV infection to prevent opportunistic and debilitating secondary problems include administration of
- A. isoniazid (INH) to prevent tuberculosis
- B. trimethoprim/sulfamethoxazole (TMP/SMX) for toxoplasmosis
- C. vaccines for pneumococcal pneumonia, influenza, and hepatitis A and B
- D. varicella-zoster immune globulin (VZIG) to prevent chickenpox or shingles
Correct Answer: C
Rationale: Vaccination protects against preventable infections that can become severe in immunocompromised individuals.